FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS
Provided herein are fatty acid amide (FAAH) cleavable prodrugs of thyromimetics and pharmaceutical compositions comprising these compounds with at least one pharmaceutically acceptable excipient further comprising a peripherally restricted FAAH inhibitor. La présente invention concerne des promédica...
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| creator | STEARNS, Brian Andrew HARRIS, Jason Randall BACCEI, Jill Melissa |
| description | Provided herein are fatty acid amide (FAAH) cleavable prodrugs of thyromimetics and pharmaceutical compositions comprising these compounds with at least one pharmaceutically acceptable excipient further comprising a peripherally restricted FAAH inhibitor.
La présente invention concerne des promédicaments clivables d'hydrolase des amides d'acides gras (FAAH) de thyromimétiques et des compositions pharmaceutiques comprenant ces composés avec au moins un excipient pharmaceutiquement acceptable comprenant en outre un inhibiteur de FAAH à restriction périphérique. |
| format | Patent |
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La présente invention concerne des promédicaments clivables d'hydrolase des amides d'acides gras (FAAH) de thyromimétiques et des compositions pharmaceutiques comprenant ces composés avec au moins un excipient pharmaceutiquement acceptable comprenant en outre un inhibiteur de FAAH à restriction périphérique.</description><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221110&DB=EPODOC&CC=WO&NR=2022236133A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221110&DB=EPODOC&CC=WO&NR=2022236133A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>STEARNS, Brian Andrew</creatorcontrib><creatorcontrib>HARRIS, Jason Randall</creatorcontrib><creatorcontrib>BACCEI, Jill Melissa</creatorcontrib><title>FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS</title><description>Provided herein are fatty acid amide (FAAH) cleavable prodrugs of thyromimetics and pharmaceutical compositions comprising these compounds with at least one pharmaceutically acceptable excipient further comprising a peripherally restricted FAAH inhibitor.
La présente invention concerne des promédicaments clivables d'hydrolase des amides d'acides gras (FAAH) de thyromimétiques et des compositions pharmaceutiques comprenant ces composés avec au moins un excipient pharmaceutiquement acceptable comprenant en outre un inhibiteur de FAAH à restriction périphérique.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNzDEKwkAQQNE0FqLeYcBGC0ETsJ_sTtyBTTbMjoZUIrJWooF4Ak8uggew-s3jT7N3hao9oGELWLMlcL2V4DESrCpEtwbjCU9YeoJWgpXjIUKoQF0voeaalE0EbCyYUJfcoHJooGN10JJw60jQ-x6EogobJQvfLXDjuGQNEufZ5Ha5j2nx6yxbVqTGbdLwPKdxuFzTI73OXci3eZ4X-11R4K74T30AqWk9gA</recordid><startdate>20221110</startdate><enddate>20221110</enddate><creator>STEARNS, Brian Andrew</creator><creator>HARRIS, Jason Randall</creator><creator>BACCEI, Jill Melissa</creator><scope>EVB</scope></search><sort><creationdate>20221110</creationdate><title>FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS</title><author>STEARNS, Brian Andrew ; HARRIS, Jason Randall ; BACCEI, Jill Melissa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022236133A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>STEARNS, Brian Andrew</creatorcontrib><creatorcontrib>HARRIS, Jason Randall</creatorcontrib><creatorcontrib>BACCEI, Jill Melissa</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>STEARNS, Brian Andrew</au><au>HARRIS, Jason Randall</au><au>BACCEI, Jill Melissa</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS</title><date>2022-11-10</date><risdate>2022</risdate><abstract>Provided herein are fatty acid amide (FAAH) cleavable prodrugs of thyromimetics and pharmaceutical compositions comprising these compounds with at least one pharmaceutically acceptable excipient further comprising a peripherally restricted FAAH inhibitor.
La présente invention concerne des promédicaments clivables d'hydrolase des amides d'acides gras (FAAH) de thyromimétiques et des compositions pharmaceutiques comprenant ces composés avec au moins un excipient pharmaceutiquement acceptable comprenant en outre un inhibiteur de FAAH à restriction périphérique.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS |
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