HYALURONIC ACID-PRODUCING RECOMBINANT CELLS

The present invention relates to the field of bio-production of hyaluronic acid. There is a need in the art for hyaluronic acid production methods allowing its highly efficient synthesis and secretion. The solution proposed in the present invention is the use of a genetically modified cell comprisin...

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Hauptverfasser: JAILLARDON, Karine, BEVILACQUA, Valentina, THOMAS, Dominique, DURANT, Lionel, LOUIS, Dominique
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creator JAILLARDON, Karine
BEVILACQUA, Valentina
THOMAS, Dominique
DURANT, Lionel
LOUIS, Dominique
description The present invention relates to the field of bio-production of hyaluronic acid. There is a need in the art for hyaluronic acid production methods allowing its highly efficient synthesis and secretion. The solution proposed in the present invention is the use of a genetically modified cell comprising many modifications as described in the present text. The present invention further proposes methods allowing the bio-production of hyaluronic acid having a controlled molecular weight using the genetically modified cells of the invention. La présente invention concerne le domaine de la bio-production d'acide hyaluronique. Il existe un besoin dans le secteur des procédés de production d'acide hyaluronique permettant sa synthèse et sa sécrétion hautement efficaces. La solution proposée dans la présente invention concerne l'utilisation d'une cellule génétiquement modifiée comprenant de nombreuses modifications telles que décrites dans la présente invention. La présente invention propose en outre des procédés permettant la bio-production d'acide hyaluronique ayant un poids moléculaire régulé à l'aide des cellules génétiquement modifiées de la présente invention.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title HYALURONIC ACID-PRODUCING RECOMBINANT CELLS
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