TRANSMEMBRANE NEOANTIGENIC PEPTIDES
The present disclosure provides transmembrane chimeric proteins derived from transposable element (TE)-exon fusion transcripts, as well as nucleic acids, antibodies, CARs, non-HLA restricted TCR and immune cells targeting such chimeric proteins that can be used in cancer therapy. La présente inventi...
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| creator | BURBAGE, Marianne STERN, Marc-Henri SADACCA, Benjamin LOPEZ LASTRA, Silvia AMIGORENA, Sebastian MERLOTTI IPPOLITO, Antonela ARRIBAS DE SANDOVAL, Yagos HOUY, Alexandre WATERFALL, Joshua GOUDOT, Christel |
| description | The present disclosure provides transmembrane chimeric proteins derived from transposable element (TE)-exon fusion transcripts, as well as nucleic acids, antibodies, CARs, non-HLA restricted TCR and immune cells targeting such chimeric proteins that can be used in cancer therapy.
La présente invention concerne des protéines chimériques transmembranaires dérivées de produits de transcription de fusion (TE)-exon à élément transposable, ainsi que des acides nucléiques, des anticorps, des CAR, des TCR restreints non HLA et des cellules immunitaires ciblant de telles protéines chimériques qui peuvent être utilisées dans une thérapie anticancéreuse. |
| format | Patent |
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La présente invention concerne des protéines chimériques transmembranaires dérivées de produits de transcription de fusion (TE)-exon à élément transposable, ainsi que des acides nucléiques, des anticorps, des CAR, des TCR restreints non HLA et des cellules immunitaires ciblant de telles protéines chimériques qui peuvent être utilisées dans une thérapie anticancéreuse.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220915&DB=EPODOC&CC=WO&NR=2022189620A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220915&DB=EPODOC&CC=WO&NR=2022189620A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BURBAGE, Marianne</creatorcontrib><creatorcontrib>STERN, Marc-Henri</creatorcontrib><creatorcontrib>SADACCA, Benjamin</creatorcontrib><creatorcontrib>LOPEZ LASTRA, Silvia</creatorcontrib><creatorcontrib>AMIGORENA, Sebastian</creatorcontrib><creatorcontrib>MERLOTTI IPPOLITO, Antonela</creatorcontrib><creatorcontrib>ARRIBAS DE SANDOVAL, Yagos</creatorcontrib><creatorcontrib>HOUY, Alexandre</creatorcontrib><creatorcontrib>WATERFALL, Joshua</creatorcontrib><creatorcontrib>GOUDOT, Christel</creatorcontrib><title>TRANSMEMBRANE NEOANTIGENIC PEPTIDES</title><description>The present disclosure provides transmembrane chimeric proteins derived from transposable element (TE)-exon fusion transcripts, as well as nucleic acids, antibodies, CARs, non-HLA restricted TCR and immune cells targeting such chimeric proteins that can be used in cancer therapy.
La présente invention concerne des protéines chimériques transmembranaires dérivées de produits de transcription de fusion (TE)-exon à élément transposable, ainsi que des acides nucléiques, des anticorps, des CAR, des TCR restreints non HLA et des cellules immunitaires ciblant de telles protéines chimériques qui peuvent être utilisées dans une thérapie anticancéreuse.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAOCXL0C_Z19XUC0q4Kfq7-jn4hnu6ufp7OCgGuASGeLq7BPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7UkPtzfyMDIyNDC0szIwNHQmDhVAP5xI9s</recordid><startdate>20220915</startdate><enddate>20220915</enddate><creator>BURBAGE, Marianne</creator><creator>STERN, Marc-Henri</creator><creator>SADACCA, Benjamin</creator><creator>LOPEZ LASTRA, Silvia</creator><creator>AMIGORENA, Sebastian</creator><creator>MERLOTTI IPPOLITO, Antonela</creator><creator>ARRIBAS DE SANDOVAL, Yagos</creator><creator>HOUY, Alexandre</creator><creator>WATERFALL, Joshua</creator><creator>GOUDOT, Christel</creator><scope>EVB</scope></search><sort><creationdate>20220915</creationdate><title>TRANSMEMBRANE NEOANTIGENIC PEPTIDES</title><author>BURBAGE, Marianne ; STERN, Marc-Henri ; SADACCA, Benjamin ; LOPEZ LASTRA, Silvia ; AMIGORENA, Sebastian ; MERLOTTI IPPOLITO, Antonela ; ARRIBAS DE SANDOVAL, Yagos ; HOUY, Alexandre ; WATERFALL, Joshua ; GOUDOT, Christel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022189620A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>BURBAGE, Marianne</creatorcontrib><creatorcontrib>STERN, Marc-Henri</creatorcontrib><creatorcontrib>SADACCA, Benjamin</creatorcontrib><creatorcontrib>LOPEZ LASTRA, Silvia</creatorcontrib><creatorcontrib>AMIGORENA, Sebastian</creatorcontrib><creatorcontrib>MERLOTTI IPPOLITO, Antonela</creatorcontrib><creatorcontrib>ARRIBAS DE SANDOVAL, Yagos</creatorcontrib><creatorcontrib>HOUY, Alexandre</creatorcontrib><creatorcontrib>WATERFALL, Joshua</creatorcontrib><creatorcontrib>GOUDOT, Christel</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BURBAGE, Marianne</au><au>STERN, Marc-Henri</au><au>SADACCA, Benjamin</au><au>LOPEZ LASTRA, Silvia</au><au>AMIGORENA, Sebastian</au><au>MERLOTTI IPPOLITO, Antonela</au><au>ARRIBAS DE SANDOVAL, Yagos</au><au>HOUY, Alexandre</au><au>WATERFALL, Joshua</au><au>GOUDOT, Christel</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TRANSMEMBRANE NEOANTIGENIC PEPTIDES</title><date>2022-09-15</date><risdate>2022</risdate><abstract>The present disclosure provides transmembrane chimeric proteins derived from transposable element (TE)-exon fusion transcripts, as well as nucleic acids, antibodies, CARs, non-HLA restricted TCR and immune cells targeting such chimeric proteins that can be used in cancer therapy.
La présente invention concerne des protéines chimériques transmembranaires dérivées de produits de transcription de fusion (TE)-exon à élément transposable, ainsi que des acides nucléiques, des anticorps, des CAR, des TCR restreints non HLA et des cellules immunitaires ciblant de telles protéines chimériques qui peuvent être utilisées dans une thérapie anticancéreuse.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | TRANSMEMBRANE NEOANTIGENIC PEPTIDES |
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