DIHYDROERGOTAMINE DRY POWER FORMULATIONS AND METHODS OF USE
The present disclosure relates to dry powder formulations comprising respirable dry particles that comprise 1) dihydroergotamine (DHE) or a salt, hydrate, or polymorph thereof, 2) a monovalent metal cation salt, and 3) one or more excipients; and also relates to methods of using the dry powder for t...
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| creator | HANSON, Dayna STOLZ, Eric CURRAN, Aidan GONZALEZ NELSON, Aaron PERRY, Jason BERGSON, Hillary |
| description | The present disclosure relates to dry powder formulations comprising respirable dry particles that comprise 1) dihydroergotamine (DHE) or a salt, hydrate, or polymorph thereof, 2) a monovalent metal cation salt, and 3) one or more excipients; and also relates to methods of using the dry powder for the treatment of a migraine, headache, or a symptom thereof, methods of making the dry powder, and receptacles and devices containing the dry powder.
La présente divulgation concerne des formulations de poudre sèche comprenant des particules sèches respirables qui comprennent 1) de la dihydroergotamine (DHE) ou un sel, un hydrate, ou un polymorphe de celle-ci, 2) un sel de cation métallique monovalent, et 3) un ou plusieurs excipients ; et qui concerne également des procédés d'utilisation de la poudre sèche pour le traitement d'une migraine, d'un mal de tête, ou d'un symptôme de ceux-ci, des procédés de fabrication de la poudre sèche, et des réceptacles et des dispositifs contenant la poudre sèche. |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | DIHYDROERGOTAMINE DRY POWER FORMULATIONS AND METHODS OF USE |
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