ANTI-SIGLEC15 ANTIBODY AND USE THEREOF
Provided in the present application is an anti-Siglec 15 antibody or an antigen-binding fragment thereof, a pharmaceutical composition and immunoconjugate comprising the antibody or antigen-binding fragment, a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a vec...
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| creator | LIU, Boning ZOU, Ruya YUAN, Can LI, Wenbin SUN, Qing HUI, Xiwu YAO, Bing DING, Huandi WANG, Yancui |
| description | Provided in the present application is an anti-Siglec 15 antibody or an antigen-binding fragment thereof, a pharmaceutical composition and immunoconjugate comprising the antibody or antigen-binding fragment, a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a vector comprising the nucleic acid molecule, a host cell comprising the vector, a method for preparing the antibody or antigen-binding fragment, and the biological medical use of the antibody or antigen-binding fragment. The use comprises regulating the immune response, reversing the inhibition of PBMC lymphocyte proliferation by the Siglec15 protein or treating tumors associated with abnormal Siglec 15 expression.
La présente invention concerne un anticorps anti-Siglec 15 ou un fragment de liaison à l'antigène de celui-ci, une composition pharmaceutique et un immunoconjugué comprenant l'anticorps ou le fragment de liaison à l'antigène, une molécule d'acide nucléique codant pour l'anticorps ou le fragment de liaison à |
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La présente invention concerne un anticorps anti-Siglec 15 ou un fragment de liaison à l'antigène de celui-ci, une composition pharmaceutique et un immunoconjugué comprenant l'anticorps ou le fragment de liaison à l'antigène, une molécule d'acide nucléique codant pour l'anticorps ou le fragment de liaison à</description><language>chi ; eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220901&DB=EPODOC&CC=WO&NR=2022179466A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220901&DB=EPODOC&CC=WO&NR=2022179466A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIU, Boning</creatorcontrib><creatorcontrib>ZOU, Ruya</creatorcontrib><creatorcontrib>YUAN, Can</creatorcontrib><creatorcontrib>LI, Wenbin</creatorcontrib><creatorcontrib>SUN, Qing</creatorcontrib><creatorcontrib>HUI, Xiwu</creatorcontrib><creatorcontrib>YAO, Bing</creatorcontrib><creatorcontrib>DING, Huandi</creatorcontrib><creatorcontrib>WANG, Yancui</creatorcontrib><title>ANTI-SIGLEC15 ANTIBODY AND USE THEREOF</title><description>Provided in the present application is an anti-Siglec 15 antibody or an antigen-binding fragment thereof, a pharmaceutical composition and immunoconjugate comprising the antibody or antigen-binding fragment, a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a vector comprising the nucleic acid molecule, a host cell comprising the vector, a method for preparing the antibody or antigen-binding fragment, and the biological medical use of the antibody or antigen-binding fragment. The use comprises regulating the immune response, reversing the inhibition of PBMC lymphocyte proliferation by the Siglec15 protein or treating tumors associated with abnormal Siglec 15 expression.
La présente invention concerne un anticorps anti-Siglec 15 ou un fragment de liaison à l'antigène de celui-ci, une composition pharmaceutique et un immunoconjugué comprenant l'anticorps ou le fragment de liaison à l'antigène, une molécule d'acide nucléique codant pour l'anticorps ou le fragment de liaison à</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBz9Avx1A32dPdxdTY0VQDxnPxdIoEMF4XQYFeFEA_XIFd_Nx4G1rTEnOJUXijNzaDs5hri7KGbWpAfn1pckJicmpdaEh_ub2RgZGRobmliZuZoaEycKgAomiQo</recordid><startdate>20220901</startdate><enddate>20220901</enddate><creator>LIU, Boning</creator><creator>ZOU, Ruya</creator><creator>YUAN, Can</creator><creator>LI, Wenbin</creator><creator>SUN, Qing</creator><creator>HUI, Xiwu</creator><creator>YAO, Bing</creator><creator>DING, Huandi</creator><creator>WANG, Yancui</creator><scope>EVB</scope></search><sort><creationdate>20220901</creationdate><title>ANTI-SIGLEC15 ANTIBODY AND USE THEREOF</title><author>LIU, Boning ; ZOU, Ruya ; YUAN, Can ; LI, Wenbin ; SUN, Qing ; HUI, Xiwu ; YAO, Bing ; DING, Huandi ; WANG, Yancui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022179466A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LIU, Boning</creatorcontrib><creatorcontrib>ZOU, Ruya</creatorcontrib><creatorcontrib>YUAN, Can</creatorcontrib><creatorcontrib>LI, Wenbin</creatorcontrib><creatorcontrib>SUN, Qing</creatorcontrib><creatorcontrib>HUI, Xiwu</creatorcontrib><creatorcontrib>YAO, Bing</creatorcontrib><creatorcontrib>DING, Huandi</creatorcontrib><creatorcontrib>WANG, Yancui</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIU, Boning</au><au>ZOU, Ruya</au><au>YUAN, Can</au><au>LI, Wenbin</au><au>SUN, Qing</au><au>HUI, Xiwu</au><au>YAO, Bing</au><au>DING, Huandi</au><au>WANG, Yancui</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTI-SIGLEC15 ANTIBODY AND USE THEREOF</title><date>2022-09-01</date><risdate>2022</risdate><abstract>Provided in the present application is an anti-Siglec 15 antibody or an antigen-binding fragment thereof, a pharmaceutical composition and immunoconjugate comprising the antibody or antigen-binding fragment, a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a vector comprising the nucleic acid molecule, a host cell comprising the vector, a method for preparing the antibody or antigen-binding fragment, and the biological medical use of the antibody or antigen-binding fragment. The use comprises regulating the immune response, reversing the inhibition of PBMC lymphocyte proliferation by the Siglec15 protein or treating tumors associated with abnormal Siglec 15 expression.
La présente invention concerne un anticorps anti-Siglec 15 ou un fragment de liaison à l'antigène de celui-ci, une composition pharmaceutique et un immunoconjugué comprenant l'anticorps ou le fragment de liaison à l'antigène, une molécule d'acide nucléique codant pour l'anticorps ou le fragment de liaison à</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | ANTI-SIGLEC15 ANTIBODY AND USE THEREOF |
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