SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES
The present disclosure relates to a vaccine comprising an amphiphile having the formula S-[B]-[U]-H and at least one peptide antigen conjugate having the formula selected from [S]-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-[S], wherein the amphiphile and/or the at least one peptide antigen conjugate co...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NICHOLS, Sarah COBLE, Vincent WELLES, Hugh GARLISS, Christopher Martin LYNN, Geoffrey GODDU, Robert ISHIZUKA, Andrew RAMIREZ-VALDEZ, Ramiro |
| description | The present disclosure relates to a vaccine comprising an amphiphile having the formula S-[B]-[U]-H and at least one peptide antigen conjugate having the formula selected from [S]-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-[S], wherein the amphiphile and/or the at least one peptide antigen conjugate comprises a dendron amplifier. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, an infectious disease, a cardiovascular disease, or a neurodegenerative disease.
La présente divulgation se rapporte à un vaccin comprenant un amphiphile ayant la formule S-[B]-[U]-H et au moins un conjugué d'antigène peptidique ayant la formule choisie parmi [S]-[E1]-A-[E2]-[U]-H et H-[U]-[E1]-A-[E2]-[S], l'amphiphile et/ou le ou les conjugués d'antigène peptidique comprenant un amplificateur de dendron. Le vaccin est utile dans le traitement ou la prévention d'un cancer, d'une maladie auto-immune, d'une allergie, d'une maladie infectieuse, d'une maladie cardiovasculaire ou d'une maladie neurodégénérative. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2022177993A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2022177993A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2022177993A13</originalsourceid><addsrcrecordid>eNrjZLAOdvVx03UMDnb1dfLx9HNX8HP08w9wDArxdPZxDVZwcgx2dVHw91Nw9A3w8AQiH09nhQDXgBBPF9dgHgbWtMSc4lReKM3NoOzmGuLsoZtakB-fWlyQmJyal1oSH-5vZGBkZGhubmlp7GhoTJwqAIrJKlc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES</title><source>esp@cenet</source><creator>NICHOLS, Sarah ; COBLE, Vincent ; WELLES, Hugh ; GARLISS, Christopher Martin ; LYNN, Geoffrey ; GODDU, Robert ; ISHIZUKA, Andrew ; RAMIREZ-VALDEZ, Ramiro</creator><creatorcontrib>NICHOLS, Sarah ; COBLE, Vincent ; WELLES, Hugh ; GARLISS, Christopher Martin ; LYNN, Geoffrey ; GODDU, Robert ; ISHIZUKA, Andrew ; RAMIREZ-VALDEZ, Ramiro</creatorcontrib><description>The present disclosure relates to a vaccine comprising an amphiphile having the formula S-[B]-[U]-H and at least one peptide antigen conjugate having the formula selected from [S]-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-[S], wherein the amphiphile and/or the at least one peptide antigen conjugate comprises a dendron amplifier. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, an infectious disease, a cardiovascular disease, or a neurodegenerative disease.
La présente divulgation se rapporte à un vaccin comprenant un amphiphile ayant la formule S-[B]-[U]-H et au moins un conjugué d'antigène peptidique ayant la formule choisie parmi [S]-[E1]-A-[E2]-[U]-H et H-[U]-[E1]-A-[E2]-[S], l'amphiphile et/ou le ou les conjugués d'antigène peptidique comprenant un amplificateur de dendron. Le vaccin est utile dans le traitement ou la prévention d'un cancer, d'une maladie auto-immune, d'une allergie, d'une maladie infectieuse, d'une maladie cardiovasculaire ou d'une maladie neurodégénérative.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220825&DB=EPODOC&CC=WO&NR=2022177993A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220825&DB=EPODOC&CC=WO&NR=2022177993A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NICHOLS, Sarah</creatorcontrib><creatorcontrib>COBLE, Vincent</creatorcontrib><creatorcontrib>WELLES, Hugh</creatorcontrib><creatorcontrib>GARLISS, Christopher Martin</creatorcontrib><creatorcontrib>LYNN, Geoffrey</creatorcontrib><creatorcontrib>GODDU, Robert</creatorcontrib><creatorcontrib>ISHIZUKA, Andrew</creatorcontrib><creatorcontrib>RAMIREZ-VALDEZ, Ramiro</creatorcontrib><title>SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES</title><description>The present disclosure relates to a vaccine comprising an amphiphile having the formula S-[B]-[U]-H and at least one peptide antigen conjugate having the formula selected from [S]-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-[S], wherein the amphiphile and/or the at least one peptide antigen conjugate comprises a dendron amplifier. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, an infectious disease, a cardiovascular disease, or a neurodegenerative disease.
La présente divulgation se rapporte à un vaccin comprenant un amphiphile ayant la formule S-[B]-[U]-H et au moins un conjugué d'antigène peptidique ayant la formule choisie parmi [S]-[E1]-A-[E2]-[U]-H et H-[U]-[E1]-A-[E2]-[S], l'amphiphile et/ou le ou les conjugués d'antigène peptidique comprenant un amplificateur de dendron. Le vaccin est utile dans le traitement ou la prévention d'un cancer, d'une maladie auto-immune, d'une allergie, d'une maladie infectieuse, d'une maladie cardiovasculaire ou d'une maladie neurodégénérative.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAOdvVx03UMDnb1dfLx9HNX8HP08w9wDArxdPZxDVZwcgx2dVHw91Nw9A3w8AQiH09nhQDXgBBPF9dgHgbWtMSc4lReKM3NoOzmGuLsoZtakB-fWlyQmJyal1oSH-5vZGBkZGhubmlp7GhoTJwqAIrJKlc</recordid><startdate>20220825</startdate><enddate>20220825</enddate><creator>NICHOLS, Sarah</creator><creator>COBLE, Vincent</creator><creator>WELLES, Hugh</creator><creator>GARLISS, Christopher Martin</creator><creator>LYNN, Geoffrey</creator><creator>GODDU, Robert</creator><creator>ISHIZUKA, Andrew</creator><creator>RAMIREZ-VALDEZ, Ramiro</creator><scope>EVB</scope></search><sort><creationdate>20220825</creationdate><title>SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES</title><author>NICHOLS, Sarah ; COBLE, Vincent ; WELLES, Hugh ; GARLISS, Christopher Martin ; LYNN, Geoffrey ; GODDU, Robert ; ISHIZUKA, Andrew ; RAMIREZ-VALDEZ, Ramiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022177993A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>NICHOLS, Sarah</creatorcontrib><creatorcontrib>COBLE, Vincent</creatorcontrib><creatorcontrib>WELLES, Hugh</creatorcontrib><creatorcontrib>GARLISS, Christopher Martin</creatorcontrib><creatorcontrib>LYNN, Geoffrey</creatorcontrib><creatorcontrib>GODDU, Robert</creatorcontrib><creatorcontrib>ISHIZUKA, Andrew</creatorcontrib><creatorcontrib>RAMIREZ-VALDEZ, Ramiro</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NICHOLS, Sarah</au><au>COBLE, Vincent</au><au>WELLES, Hugh</au><au>GARLISS, Christopher Martin</au><au>LYNN, Geoffrey</au><au>GODDU, Robert</au><au>ISHIZUKA, Andrew</au><au>RAMIREZ-VALDEZ, Ramiro</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES</title><date>2022-08-25</date><risdate>2022</risdate><abstract>The present disclosure relates to a vaccine comprising an amphiphile having the formula S-[B]-[U]-H and at least one peptide antigen conjugate having the formula selected from [S]-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-[S], wherein the amphiphile and/or the at least one peptide antigen conjugate comprises a dendron amplifier. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, an infectious disease, a cardiovascular disease, or a neurodegenerative disease.
La présente divulgation se rapporte à un vaccin comprenant un amphiphile ayant la formule S-[B]-[U]-H et au moins un conjugué d'antigène peptidique ayant la formule choisie parmi [S]-[E1]-A-[E2]-[U]-H et H-[U]-[E1]-A-[E2]-[S], l'amphiphile et/ou le ou les conjugués d'antigène peptidique comprenant un amplificateur de dendron. Le vaccin est utile dans le traitement ou la prévention d'un cancer, d'une maladie auto-immune, d'une allergie, d'une maladie infectieuse, d'une maladie cardiovasculaire ou d'une maladie neurodégénérative.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2022177993A1 |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T17%3A07%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NICHOLS,%20Sarah&rft.date=2022-08-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2022177993A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |