SMALL MOLECULE INHIBITORS OF PBRM1-BD2

The present disclosure provides novel inhibitors of PBRM1, specifically the 2nd bromodomain of PBRM1 (PBRM1-BD2), pharmaceutical compositions and methods of use thereof. La présente invention concerne de nouveaux inhibiteurs de PBRM1, plus spécifiquement le 2ème bromodomaine de PBRM1 (PBRM1-BD2), de...

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Hauptverfasser:	OLP, Michael D, GOETZ, Christopher J, SHISHODIA, Shifali, SMITH, Brian Christopher
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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