ANTIBODY COMBINATION THERAPIES FOR SARS-COV-2 INFECTION
The present disclosure provides antibody combinations and related methods for treating a SARS-CoV-2 infection in a subject or for manufacturing a medicament for the treatment of a SARS-CoV-2 infection. In some aspects, a therapy, composition, or combination can include two or three antibodies that b...
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| creator | LEMPP, Florian YEH, Wendy CORTI, Davide MOGALIAN, Erik JONES, Bryan Edward HEBNER, Christy M VIRGIN, Herbert W PANG, Phillip S ADAMS, Andrew Charles |
| description | The present disclosure provides antibody combinations and related methods for treating a SARS-CoV-2 infection in a subject or for manufacturing a medicament for the treatment of a SARS-CoV-2 infection. In some aspects, a therapy, composition, or combination can include two or three antibodies that bind to different epitopes on a SARS-CoV-2 surface (S) glycoprotein. The antibody combinations can potently neutralize SARS-CoV-2. Antibody compositions comprising such combinations are also provided.
La présente divulgation concerne des combinaisons d'anticorps et des méthodes associées pour traiter une infection par SARS-CoV-2 chez un sujet ou pour fabriquer un médicament pour le traitement d'une infection par SARS-CoV-2. Dans certains aspects, une thérapie, une composition ou une combinaison peuvent comprendre deux ou trois anticorps qui se lient à différents épitopes sur une glycoprotéine de surface (S) de SARS-CoV-2. Les combinaisons d'anticorps peuvent neutraliser puissamment le SARS-CoV-2. L'invention concerne également des compositions d'anticorps comprenant de telles combinaisons. |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ANTIBODY COMBINATION THERAPIES FOR SARS-COV-2 INFECTION |
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