SUBCUTANEOUS ADMINISTRATION OF PD1/PD-L1 ANTIBODIES

The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La divulgation concerne des compo...

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Bibliographische Detailangaben
Hauptverfasser:	KHOSSRAVI, Mehrnaz, ROY, Amit, BELLO, Akintunde, ZHAO, Xiaochen, HART, Scott, VEZINA, Heather, HUANG, Masano, MANTRI, Rao, SANGHAVI, Kinjal, HABY, Thomas, MURTHY, Bindu, ARAS, Urvi
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La divulgation concerne des compositions pharmaceutiques comprenant un anticorps anti-PD-1 ou un anticorps anti-PD-L1 formulé pour une administration sous-cutanée, les compositions pharmaceutiques comprenant en outre une enzyme endoglycosidase hydrolase telle qu'une hyaluronidase.