ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF
The present invention relates to an isoxazolidine derivative compound and the use thereof. The isoxazolidine derivative compound of the present invention exhibits excellent inhibitory activity against CDK2, CDK4, CDK6 and/or HPK1, and thus can be utilized in treating or preventing diseases related t...
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| creator | RYU, Hee Sun KIM, Seung Su SON, Jung Beom KIM, Da Mi JO, Seo Hyun KIM, Sung Hwan KIM, Nam Doo |
| description | The present invention relates to an isoxazolidine derivative compound and the use thereof. The isoxazolidine derivative compound of the present invention exhibits excellent inhibitory activity against CDK2, CDK4, CDK6 and/or HPK1, and thus can be utilized in treating or preventing diseases related to CDK2, CDK4, CDK6 and/or HPK1.
La présente invention concerne un composé dérivé d'isoxazolidine et son utilisation. Le composé dérivé d'isoxazolidine de la présente invention présente une excellente activité inhibitrice contre CDK2, CDK4, CDK6 et/ou HPK1, et peut ainsi être utilisé dans le traitement ou la prévention de maladies associées à CDK2, CDK4, CDK6 et/ou HPK1.
본 발명은 아이소옥사졸리딘 유도체 화합물 및 이의 용도에 관한 것이다. 본 발명의 아이소옥사졸리딘 유도체 화합물은 CDK2, CDK4, CDK6 및/또는 HPK1에 대해 우수한 억제 활성을 나타내므로, 상기 CDK2, CDK4, CDK6 및/또는 HPK1 관련 질환의 치료 또는 예방에 유용하게 사용될 수 있다. |
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La présente invention concerne un composé dérivé d'isoxazolidine et son utilisation. Le composé dérivé d'isoxazolidine de la présente invention présente une excellente activité inhibitrice contre CDK2, CDK4, CDK6 et/ou HPK1, et peut ainsi être utilisé dans le traitement ou la prévention de maladies associées à CDK2, CDK4, CDK6 et/ou HPK1.
본 발명은 아이소옥사졸리딘 유도체 화합물 및 이의 용도에 관한 것이다. 본 발명의 아이소옥사졸리딘 유도체 화합물은 CDK2, CDK4, CDK6 및/또는 HPK1에 대해 우수한 억제 활성을 나타내므로, 상기 CDK2, CDK4, CDK6 및/또는 HPK1 관련 질환의 치료 또는 예방에 유용하게 사용될 수 있다.</description><language>eng ; fre ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220623&DB=EPODOC&CC=WO&NR=2022131741A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220623&DB=EPODOC&CC=WO&NR=2022131741A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RYU, Hee Sun</creatorcontrib><creatorcontrib>KIM, Seung Su</creatorcontrib><creatorcontrib>SON, Jung Beom</creatorcontrib><creatorcontrib>KIM, Da Mi</creatorcontrib><creatorcontrib>JO, Seo Hyun</creatorcontrib><creatorcontrib>KIM, Sung Hwan</creatorcontrib><creatorcontrib>KIM, Nam Doo</creatorcontrib><title>ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF</title><description>The present invention relates to an isoxazolidine derivative compound and the use thereof. The isoxazolidine derivative compound of the present invention exhibits excellent inhibitory activity against CDK2, CDK4, CDK6 and/or HPK1, and thus can be utilized in treating or preventing diseases related to CDK2, CDK4, CDK6 and/or HPK1.
La présente invention concerne un composé dérivé d'isoxazolidine et son utilisation. Le composé dérivé d'isoxazolidine de la présente invention présente une excellente activité inhibitrice contre CDK2, CDK4, CDK6 et/ou HPK1, et peut ainsi être utilisé dans le traitement ou la prévention de maladies associées à CDK2, CDK4, CDK6 et/ou HPK1.
본 발명은 아이소옥사졸리딘 유도체 화합물 및 이의 용도에 관한 것이다. 본 발명의 아이소옥사졸리딘 유도체 화합물은 CDK2, CDK4, CDK6 및/또는 HPK1에 대해 우수한 억제 활성을 나타내므로, 상기 CDK2, CDK4, CDK6 및/또는 HPK1 관련 질환의 치료 또는 예방에 유용하게 사용될 수 있다.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDD0DPaPcIzy9_F08fRzVXBxDfIMcwzxDHNVcPb3DfAP9XNRcATi0GBXhRAP1yBXfzceBta0xJziVF4ozc2g7OYa4uyhm1qQH59aXJCYnJqXWhIf7m9kYGRkaGxobmLoaGhMnCoACl0nnQ</recordid><startdate>20220623</startdate><enddate>20220623</enddate><creator>RYU, Hee Sun</creator><creator>KIM, Seung Su</creator><creator>SON, Jung Beom</creator><creator>KIM, Da Mi</creator><creator>JO, Seo Hyun</creator><creator>KIM, Sung Hwan</creator><creator>KIM, Nam Doo</creator><scope>EVB</scope></search><sort><creationdate>20220623</creationdate><title>ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF</title><author>RYU, Hee Sun ; KIM, Seung Su ; SON, Jung Beom ; KIM, Da Mi ; JO, Seo Hyun ; KIM, Sung Hwan ; KIM, Nam Doo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022131741A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; kor</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RYU, Hee Sun</creatorcontrib><creatorcontrib>KIM, Seung Su</creatorcontrib><creatorcontrib>SON, Jung Beom</creatorcontrib><creatorcontrib>KIM, Da Mi</creatorcontrib><creatorcontrib>JO, Seo Hyun</creatorcontrib><creatorcontrib>KIM, Sung Hwan</creatorcontrib><creatorcontrib>KIM, Nam Doo</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RYU, Hee Sun</au><au>KIM, Seung Su</au><au>SON, Jung Beom</au><au>KIM, Da Mi</au><au>JO, Seo Hyun</au><au>KIM, Sung Hwan</au><au>KIM, Nam Doo</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF</title><date>2022-06-23</date><risdate>2022</risdate><abstract>The present invention relates to an isoxazolidine derivative compound and the use thereof. The isoxazolidine derivative compound of the present invention exhibits excellent inhibitory activity against CDK2, CDK4, CDK6 and/or HPK1, and thus can be utilized in treating or preventing diseases related to CDK2, CDK4, CDK6 and/or HPK1.
La présente invention concerne un composé dérivé d'isoxazolidine et son utilisation. Le composé dérivé d'isoxazolidine de la présente invention présente une excellente activité inhibitrice contre CDK2, CDK4, CDK6 et/ou HPK1, et peut ainsi être utilisé dans le traitement ou la prévention de maladies associées à CDK2, CDK4, CDK6 et/ou HPK1.
본 발명은 아이소옥사졸리딘 유도체 화합물 및 이의 용도에 관한 것이다. 본 발명의 아이소옥사졸리딘 유도체 화합물은 CDK2, CDK4, CDK6 및/또는 HPK1에 대해 우수한 억제 활성을 나타내므로, 상기 CDK2, CDK4, CDK6 및/또는 HPK1 관련 질환의 치료 또는 예방에 유용하게 사용될 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF |
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