TECHNIQUE FOR DIAGNOSING STRESS ASSOCIATED WITH ATOPIC DERMATITIS USING EXOSOME-DERIVED MIRNAS
The present invention comprises analyzing miRNAs derived from exosomes of a mouse in which stress was induced by atopic dermatitis, and then confirming that the expression patterns of a plurality of the miRNAs changed after the stress-inducing treatment compared to before the treatment, thereby deri...
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| creator | KANG, Kyung Ku LEE, Si Joon SUNG, Soo Eun CHOI, Joo Hee KIM, Kil Soo WOO, Jungmin SEO, Min Soo SUNG, Min Kyoung |
| description | The present invention comprises analyzing miRNAs derived from exosomes of a mouse in which stress was induced by atopic dermatitis, and then confirming that the expression patterns of a plurality of the miRNAs changed after the stress-inducing treatment compared to before the treatment, thereby deriving that the miRNAs may be used as a biomarker, and thus the present invention may be used in various related fields such as skin inflammation and stress correlation, and stress diagnosis businesses.
La présente invention comprend l'analyse des miARN dérivés des exosomes d'une souris présentant un stress induit par une dermatite atopique, puis la confirmation que les profils d'expression d'une pluralité de miARN ont changé après le traitement induisant le stress par rapport à avant le traitement, ce qui permet de déduire que les miARN peuvent être utilisés comme biomarqueur, et donc que la présente invention peut être utilisée dans divers domaines connexes tels que la corrélation entre l'inflammation cutanée et le stress, et les activités de diagnostic du stress.
본 발명은 아토피성 피부염으로 스트레스를 유발한 마우스의 엑소좀에서 유래한 miRNA를 분석한 다음, 스트레스 처리 전후에 발현양상이 달라지는 다수의 miRNA를 확인하여 이를 바이오마커로 활용 가능하다는 점을 도출하였는바, 피부염증과 스트레스의 연관성 및 스트레스 진단 사업 등 관련된 다양한 분야에 이용될 수 있다. |
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La présente invention comprend l'analyse des miARN dérivés des exosomes d'une souris présentant un stress induit par une dermatite atopique, puis la confirmation que les profils d'expression d'une pluralité de miARN ont changé après le traitement induisant le stress par rapport à avant le traitement, ce qui permet de déduire que les miARN peuvent être utilisés comme biomarqueur, et donc que la présente invention peut être utilisée dans divers domaines connexes tels que la corrélation entre l'inflammation cutanée et le stress, et les activités de diagnostic du stress.
본 발명은 아토피성 피부염으로 스트레스를 유발한 마우스의 엑소좀에서 유래한 miRNA를 분석한 다음, 스트레스 처리 전후에 발현양상이 달라지는 다수의 miRNA를 확인하여 이를 바이오마커로 활용 가능하다는 점을 도출하였는바, 피부염증과 스트레스의 연관성 및 스트레스 진단 사업 등 관련된 다양한 분야에 이용될 수 있다.</description><language>eng ; fre ; kor</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220519&DB=EPODOC&CC=WO&NR=2022102885A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220519&DB=EPODOC&CC=WO&NR=2022102885A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KANG, Kyung Ku</creatorcontrib><creatorcontrib>LEE, Si Joon</creatorcontrib><creatorcontrib>SUNG, Soo Eun</creatorcontrib><creatorcontrib>CHOI, Joo Hee</creatorcontrib><creatorcontrib>KIM, Kil Soo</creatorcontrib><creatorcontrib>WOO, Jungmin</creatorcontrib><creatorcontrib>SEO, Min Soo</creatorcontrib><creatorcontrib>SUNG, Min Kyoung</creatorcontrib><title>TECHNIQUE FOR DIAGNOSING STRESS ASSOCIATED WITH ATOPIC DERMATITIS USING EXOSOME-DERIVED MIRNAS</title><description>The present invention comprises analyzing miRNAs derived from exosomes of a mouse in which stress was induced by atopic dermatitis, and then confirming that the expression patterns of a plurality of the miRNAs changed after the stress-inducing treatment compared to before the treatment, thereby deriving that the miRNAs may be used as a biomarker, and thus the present invention may be used in various related fields such as skin inflammation and stress correlation, and stress diagnosis businesses.
La présente invention comprend l'analyse des miARN dérivés des exosomes d'une souris présentant un stress induit par une dermatite atopique, puis la confirmation que les profils d'expression d'une pluralité de miARN ont changé après le traitement induisant le stress par rapport à avant le traitement, ce qui permet de déduire que les miARN peuvent être utilisés comme biomarqueur, et donc que la présente invention peut être utilisée dans divers domaines connexes tels que la corrélation entre l'inflammation cutanée et le stress, et les activités de diagnostic du stress.
본 발명은 아토피성 피부염으로 스트레스를 유발한 마우스의 엑소좀에서 유래한 miRNA를 분석한 다음, 스트레스 처리 전후에 발현양상이 달라지는 다수의 miRNA를 확인하여 이를 바이오마커로 활용 가능하다는 점을 도출하였는바, 피부염증과 스트레스의 연관성 및 스트레스 진단 사업 등 관련된 다양한 분야에 이용될 수 있다.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNysEKgkAQgGEvHaJ6h4HOgm4EXYd11Dm4WztjdkoktlOUYO9PEj1Ap__wf8vkqmRrx6eWoPQBCsbKeWFXgWggEUARbxmVCuhYa0D1R7ZQUGhQWVmg_XK6ePENpfPg84wbDg5lnSzuw2OKm19XybYktXUax1cfp3G4xWd89503mTF5Zg6HPea7_9QHIHE0Nw</recordid><startdate>20220519</startdate><enddate>20220519</enddate><creator>KANG, Kyung Ku</creator><creator>LEE, Si Joon</creator><creator>SUNG, Soo Eun</creator><creator>CHOI, Joo Hee</creator><creator>KIM, Kil Soo</creator><creator>WOO, Jungmin</creator><creator>SEO, Min Soo</creator><creator>SUNG, Min Kyoung</creator><scope>EVB</scope></search><sort><creationdate>20220519</creationdate><title>TECHNIQUE FOR DIAGNOSING STRESS ASSOCIATED WITH ATOPIC DERMATITIS USING EXOSOME-DERIVED MIRNAS</title><author>KANG, Kyung Ku ; LEE, Si Joon ; SUNG, Soo Eun ; CHOI, Joo Hee ; KIM, Kil Soo ; WOO, Jungmin ; SEO, Min Soo ; SUNG, Min Kyoung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022102885A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; kor</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KANG, Kyung Ku</creatorcontrib><creatorcontrib>LEE, Si Joon</creatorcontrib><creatorcontrib>SUNG, Soo Eun</creatorcontrib><creatorcontrib>CHOI, Joo Hee</creatorcontrib><creatorcontrib>KIM, Kil Soo</creatorcontrib><creatorcontrib>WOO, Jungmin</creatorcontrib><creatorcontrib>SEO, Min Soo</creatorcontrib><creatorcontrib>SUNG, Min Kyoung</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KANG, Kyung Ku</au><au>LEE, Si Joon</au><au>SUNG, Soo Eun</au><au>CHOI, Joo Hee</au><au>KIM, Kil Soo</au><au>WOO, Jungmin</au><au>SEO, Min Soo</au><au>SUNG, Min Kyoung</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TECHNIQUE FOR DIAGNOSING STRESS ASSOCIATED WITH ATOPIC DERMATITIS USING EXOSOME-DERIVED MIRNAS</title><date>2022-05-19</date><risdate>2022</risdate><abstract>The present invention comprises analyzing miRNAs derived from exosomes of a mouse in which stress was induced by atopic dermatitis, and then confirming that the expression patterns of a plurality of the miRNAs changed after the stress-inducing treatment compared to before the treatment, thereby deriving that the miRNAs may be used as a biomarker, and thus the present invention may be used in various related fields such as skin inflammation and stress correlation, and stress diagnosis businesses.
La présente invention comprend l'analyse des miARN dérivés des exosomes d'une souris présentant un stress induit par une dermatite atopique, puis la confirmation que les profils d'expression d'une pluralité de miARN ont changé après le traitement induisant le stress par rapport à avant le traitement, ce qui permet de déduire que les miARN peuvent être utilisés comme biomarqueur, et donc que la présente invention peut être utilisée dans divers domaines connexes tels que la corrélation entre l'inflammation cutanée et le stress, et les activités de diagnostic du stress.
본 발명은 아토피성 피부염으로 스트레스를 유발한 마우스의 엑소좀에서 유래한 miRNA를 분석한 다음, 스트레스 처리 전후에 발현양상이 달라지는 다수의 miRNA를 확인하여 이를 바이오마커로 활용 가능하다는 점을 도출하였는바, 피부염증과 스트레스의 연관성 및 스트레스 진단 사업 등 관련된 다양한 분야에 이용될 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | TECHNIQUE FOR DIAGNOSING STRESS ASSOCIATED WITH ATOPIC DERMATITIS USING EXOSOME-DERIVED MIRNAS |
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