NOVEL OMNI-50 CRISPR NUCLEASE-RNA COMPLEXES
A composition comprising a non-naturally occurring RNA molecule, the RNA molecule comprising an RNA scaffold portion, the RNA scaffold portion having the structure: crRNA repeat sequence portion - Linker portion - tracrRNA portion; wherein the RNA scaffold portion forms a complex with and targets an...
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| creator | MARBACH BAR, Nadav IZHAR, Lior ROCKAH, Liat |
| description | A composition comprising a non-naturally occurring RNA molecule, the RNA molecule comprising an RNA scaffold portion, the RNA scaffold portion having the structure: crRNA repeat sequence portion - Linker portion - tracrRNA portion; wherein the RNA scaffold portion forms a complex with and targets an OMNI-50 CRISPR nuclease to a DNA target site having complementarity to a guide sequence portion of the RNA molecule.
Composition comprenant une molécule d'ARN d'origine non naturelle, la molécule d'ARN comprenant une partie d'échafaudage d'ARN, la partie d'échafaudage d'ARN ayant la structure suivante : une portion de séquence répétée d'ARNcr - une portion de lieur - une portion d'ARNtracr; dans laquelle la partie d'échafaudage d'ARN forme un complexe avec et cible une nucléase CRISPR OMNI-50 vers un site cible d'ADN ayant une complémentarité avec une portion de séquence guide de la molécule d'ARN. |
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Composition comprenant une molécule d'ARN d'origine non naturelle, la molécule d'ARN comprenant une partie d'échafaudage d'ARN, la partie d'échafaudage d'ARN ayant la structure suivante : une portion de séquence répétée d'ARNcr - une portion de lieur - une portion d'ARNtracr; dans laquelle la partie d'échafaudage d'ARN forme un complexe avec et cible une nucléase CRISPR OMNI-50 vers un site cible d'ADN ayant une complémentarité avec une portion de séquence guide de la molécule d'ARN.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220512&DB=EPODOC&CC=WO&NR=2022098693A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220512&DB=EPODOC&CC=WO&NR=2022098693A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MARBACH BAR, Nadav</creatorcontrib><creatorcontrib>IZHAR, Lior</creatorcontrib><creatorcontrib>ROCKAH, Liat</creatorcontrib><title>NOVEL OMNI-50 CRISPR NUCLEASE-RNA COMPLEXES</title><description>A composition comprising a non-naturally occurring RNA molecule, the RNA molecule comprising an RNA scaffold portion, the RNA scaffold portion having the structure: crRNA repeat sequence portion - Linker portion - tracrRNA portion; wherein the RNA scaffold portion forms a complex with and targets an OMNI-50 CRISPR nuclease to a DNA target site having complementarity to a guide sequence portion of the RNA molecule.
Composition comprenant une molécule d'ARN d'origine non naturelle, la molécule d'ARN comprenant une partie d'échafaudage d'ARN, la partie d'échafaudage d'ARN ayant la structure suivante : une portion de séquence répétée d'ARNcr - une portion de lieur - une portion d'ARNtracr; dans laquelle la partie d'échafaudage d'ARN forme un complexe avec et cible une nucléase CRISPR OMNI-50 vers un site cible d'ADN ayant une complémentarité avec une portion de séquence guide de la molécule d'ARN.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND28w9z9VHw9_Xz1DU1UHAO8gwOCFLwC3X2cXUMdtUN8nNUcPb3DfBxjXAN5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgZGRgaWFmaWxo6GxsSpAgDz5iW-</recordid><startdate>20220512</startdate><enddate>20220512</enddate><creator>MARBACH BAR, Nadav</creator><creator>IZHAR, Lior</creator><creator>ROCKAH, Liat</creator><scope>EVB</scope></search><sort><creationdate>20220512</creationdate><title>NOVEL OMNI-50 CRISPR NUCLEASE-RNA COMPLEXES</title><author>MARBACH BAR, Nadav ; IZHAR, Lior ; ROCKAH, Liat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022098693A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MARBACH BAR, Nadav</creatorcontrib><creatorcontrib>IZHAR, Lior</creatorcontrib><creatorcontrib>ROCKAH, Liat</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MARBACH BAR, Nadav</au><au>IZHAR, Lior</au><au>ROCKAH, Liat</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL OMNI-50 CRISPR NUCLEASE-RNA COMPLEXES</title><date>2022-05-12</date><risdate>2022</risdate><abstract>A composition comprising a non-naturally occurring RNA molecule, the RNA molecule comprising an RNA scaffold portion, the RNA scaffold portion having the structure: crRNA repeat sequence portion - Linker portion - tracrRNA portion; wherein the RNA scaffold portion forms a complex with and targets an OMNI-50 CRISPR nuclease to a DNA target site having complementarity to a guide sequence portion of the RNA molecule.
Composition comprenant une molécule d'ARN d'origine non naturelle, la molécule d'ARN comprenant une partie d'échafaudage d'ARN, la partie d'échafaudage d'ARN ayant la structure suivante : une portion de séquence répétée d'ARNcr - une portion de lieur - une portion d'ARNtracr; dans laquelle la partie d'échafaudage d'ARN forme un complexe avec et cible une nucléase CRISPR OMNI-50 vers un site cible d'ADN ayant une complémentarité avec une portion de séquence guide de la molécule d'ARN.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | NOVEL OMNI-50 CRISPR NUCLEASE-RNA COMPLEXES |
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