SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF
A compound represented by formula (I), and a racemate, a stereoisomer, a tautomer, an isotopic label, an N-oxide, a hydrate, a solvate, a polymorph, a metabolite, a pharmaceutically acceptable salt, a pharmaceutically acceptable ester, or a prodrug compound thereof. This class of compounds has a goo...
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Format: | Patent |
Sprache: | chi ; eng ; fre |
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Zusammenfassung: | A compound represented by formula (I), and a racemate, a stereoisomer, a tautomer, an isotopic label, an N-oxide, a hydrate, a solvate, a polymorph, a metabolite, a pharmaceutically acceptable salt, a pharmaceutically acceptable ester, or a prodrug compound thereof. This class of compounds has a good LRRK2 kinase regulation and inhibition and can be used for the treatment of an LRRK2 kinase activity-associated conditions and diseases, such as proliferative diseases, protein kinase-associated diseases, lysosomal diseases, Tau diseases, and diseases caused by decreased dopamine levels, etc., and is prepared by a simple method, and has good application prospects.
L'invention concerne un composé représenté par la formule (I), et un racémate, un stéréoisomère, un tautomère, une étiquette isotopique, un N-oxyde, un hydrate, un solvate, un polymorphe, un métabolite, un sel pharmaceutiquement acceptable, un ester pharmaceutiquement acceptable, ou un composé promédicament de celui-ci. Cette classe de composés a une bo |
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