A DIAGNOSTIC KIT FOR USE IN THE DIAGNOSIS OF PHILADELPHIA CHROMOSOME-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA

A DIAGNOSTIC KIT FOR USE IN THE DIAGNOSIS OF PHILADELPHIA CHROMOSOME-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA

The invention is a diagnostic kit suitable for use in the diagnosis of Philadelphia-like acute lymphoblastic leukemia comprising the following genes; CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3,...

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Hauptverfasser: TEZCAN ÜNLÜ, Havva, SEZGİN EVİM, Melike, ÜNAL, Ufuk, EFENDİ ERDEM, Ecem, ÇEÇENER, Gülşah, MERAL GÜNEŞ, Adalet, BAYTAN, Birol, EGELİ, Ünal
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creator TEZCAN ÜNLÜ, Havva
SEZGİN EVİM, Melike
ÜNAL, Ufuk
EFENDİ ERDEM, Ecem
ÇEÇENER, Gülşah
MERAL GÜNEŞ, Adalet
BAYTAN, Birol
EGELİ, Ünal
description The invention is a diagnostic kit suitable for use in the diagnosis of Philadelphia-like acute lymphoblastic leukemia comprising the following genes; CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB, and the algorithm analysis in which the similarity is determined. L'invention concerne un kit de diagnostic approprié pour être utilisé dans le diagnostic de la leucémie lymphoblastique aiguë du type Philadelphie comprenant les gènes suivants : CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB et l'analyse algorithmique dans laquelle la similarité est déterminée.
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L'invention concerne un kit de diagnostic approprié pour être utilisé dans le diagnostic de la leucémie lymphoblastique aiguë du type Philadelphie comprenant les gènes suivants : CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB et l'analyse algorithmique dans laquelle la similarité est déterminée.</description><language>eng ; fre</language><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220428&amp;DB=EPODOC&amp;CC=WO&amp;NR=2022086476A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220428&amp;DB=EPODOC&amp;CC=WO&amp;NR=2022086476A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TEZCAN ÜNLÜ, Havva</creatorcontrib><creatorcontrib>SEZGİN EVİM, Melike</creatorcontrib><creatorcontrib>ÜNAL, Ufuk</creatorcontrib><creatorcontrib>EFENDİ ERDEM, Ecem</creatorcontrib><creatorcontrib>ÇEÇENER, Gülşah</creatorcontrib><creatorcontrib>MERAL GÜNEŞ, Adalet</creatorcontrib><creatorcontrib>BAYTAN, Birol</creatorcontrib><creatorcontrib>EGELİ, Ünal</creatorcontrib><title>A DIAGNOSTIC KIT FOR USE IN THE DIAGNOSIS OF PHILADELPHIA CHROMOSOME-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA</title><description>The invention is a diagnostic kit suitable for use in the diagnosis of Philadelphia-like acute lymphoblastic leukemia comprising the following genes; CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB, and the algorithm analysis in which the similarity is determined. L'invention concerne un kit de diagnostic approprié pour être utilisé dans le diagnostic de la leucémie lymphoblastique aiguë du type Philadelphie comprenant les gènes suivants : CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB et l'analyse algorithmique dans laquelle la similarité est déterminée.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKwjAQQLs4iPoPB86FEqW6nunVHE160qSIUymSTqKF-v8oorvTG97jzZMBoWA81uIDa6g4QCkNtJ6AawiGfpY9SAknwxYLsm8iaNOIEy-OUssVAeo2ENiLOxk5WPwMLbUVOcZlMhv62xRXXy6SdUlBmzSOjy5OY3-N9_jszqIypbJ9vt3lqDb_VS9SfDXG</recordid><startdate>20220428</startdate><enddate>20220428</enddate><creator>TEZCAN ÜNLÜ, Havva</creator><creator>SEZGİN EVİM, Melike</creator><creator>ÜNAL, Ufuk</creator><creator>EFENDİ ERDEM, Ecem</creator><creator>ÇEÇENER, Gülşah</creator><creator>MERAL GÜNEŞ, Adalet</creator><creator>BAYTAN, Birol</creator><creator>EGELİ, Ünal</creator><scope>EVB</scope></search><sort><creationdate>20220428</creationdate><title>A DIAGNOSTIC KIT FOR USE IN THE DIAGNOSIS OF PHILADELPHIA CHROMOSOME-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA</title><author>TEZCAN ÜNLÜ, Havva ; SEZGİN EVİM, Melike ; ÜNAL, Ufuk ; EFENDİ ERDEM, Ecem ; ÇEÇENER, Gülşah ; MERAL GÜNEŞ, Adalet ; BAYTAN, Birol ; EGELİ, Ünal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022086476A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><toplevel>online_resources</toplevel><creatorcontrib>TEZCAN ÜNLÜ, Havva</creatorcontrib><creatorcontrib>SEZGİN EVİM, Melike</creatorcontrib><creatorcontrib>ÜNAL, Ufuk</creatorcontrib><creatorcontrib>EFENDİ ERDEM, Ecem</creatorcontrib><creatorcontrib>ÇEÇENER, Gülşah</creatorcontrib><creatorcontrib>MERAL GÜNEŞ, Adalet</creatorcontrib><creatorcontrib>BAYTAN, Birol</creatorcontrib><creatorcontrib>EGELİ, Ünal</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TEZCAN ÜNLÜ, Havva</au><au>SEZGİN EVİM, Melike</au><au>ÜNAL, Ufuk</au><au>EFENDİ ERDEM, Ecem</au><au>ÇEÇENER, Gülşah</au><au>MERAL GÜNEŞ, Adalet</au><au>BAYTAN, Birol</au><au>EGELİ, Ünal</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A DIAGNOSTIC KIT FOR USE IN THE DIAGNOSIS OF PHILADELPHIA CHROMOSOME-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA</title><date>2022-04-28</date><risdate>2022</risdate><abstract>The invention is a diagnostic kit suitable for use in the diagnosis of Philadelphia-like acute lymphoblastic leukemia comprising the following genes; CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB, and the algorithm analysis in which the similarity is determined. L'invention concerne un kit de diagnostic approprié pour être utilisé dans le diagnostic de la leucémie lymphoblastique aiguë du type Philadelphie comprenant les gènes suivants : CD99, NOTCH1, EZH2, MPL, MLLT4, BCL2, IKZF2, FBXW7, CHD1, IRF8, IDH1, CD274, ETV6, IGJ, FLT3, CREBBP, EBF1, MLL, EPOR, JAK2, KDM6A, IRF4, IKZF3, JAK3, KRAS, CRLF2, HOXA9, IL7R, ABL1, LMO1, FGFR1, NF1, IFITM1, CSF1R, CA6, IDH2, CTLA4, MUC4, IKZF1, JAK1, BCL6, AICDA, KLF2, MYC, BLNK, HOXA10, BCL11B, P2RY8, SEMA6A, SOCS1, PDCD1LG2, RUNX1, PTK2B, NUDT4, PAX5, SOCS2, PICALM, NTRK3, STIL, SH2B3, TLX3, TCF3, NRAS, WT1, TP53INP1, TAL1, PDGFRA, STAT3, PBX1, SETD2, NUP214, PDCD1, PAG1, PTPN1, PDGFRB, STAT5B, ABL2, DNM2, DNTT, LYL1, NT5C2, NUP98, PTPN11, GAPDH, RAG1, RAG2, SOX11, GPR110, TLX1, G6PD, TYK2, ZCCHC7, BCR, IFITM2, BRAF, ACTB et l'analyse algorithmique dans laquelle la similarité est déterminée.</abstract><oa>free_for_read</oa></addata></record>
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title A DIAGNOSTIC KIT FOR USE IN THE DIAGNOSIS OF PHILADELPHIA CHROMOSOME-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA
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