ORGANOID RECOMBINATION
Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be d...
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| creator | BROWN, Nicole SINGH, Akaljot SUNDARAM, Nambirajan HELMRATH, Michael VALES, Simon |
| description | Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be derived from the same or different cell type or organoid type. These organoid compositions may exhibit advantageous properties, for example, enhanced in vivo engraftment.
Sont divulguées ici des compositions d'organoïdes comprenant des combinaisons hétérogènes de constituants épithéliaux et mésenchymateux, et leurs procédés de préparation par dissociation et recombinaison des constituants épithéliaux et mésenchymateux de différentes sources. Ces constituants épithéliaux et mésenchymateux peuvent être dérivés d'un type de cellules, ou d'organoïdes, identiques ou différents. Ces compositions d'organoïdes peuvent présenter des propriétés avantageuses, par exemple, une prise de greffe in vivo améliorée. |
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Sont divulguées ici des compositions d'organoïdes comprenant des combinaisons hétérogènes de constituants épithéliaux et mésenchymateux, et leurs procédés de préparation par dissociation et recombinaison des constituants épithéliaux et mésenchymateux de différentes sources. Ces constituants épithéliaux et mésenchymateux peuvent être dérivés d'un type de cellules, ou d'organoïdes, identiques ou différents. Ces compositions d'organoïdes peuvent présenter des propriétés avantageuses, par exemple, une prise de greffe in vivo améliorée.</description><language>eng ; fre</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220407&DB=EPODOC&CC=WO&NR=2022072553A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220407&DB=EPODOC&CC=WO&NR=2022072553A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BROWN, Nicole</creatorcontrib><creatorcontrib>SINGH, Akaljot</creatorcontrib><creatorcontrib>SUNDARAM, Nambirajan</creatorcontrib><creatorcontrib>HELMRATH, Michael</creatorcontrib><creatorcontrib>VALES, Simon</creatorcontrib><title>ORGANOID RECOMBINATION</title><description>Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be derived from the same or different cell type or organoid type. These organoid compositions may exhibit advantageous properties, for example, enhanced in vivo engraftment.
Sont divulguées ici des compositions d'organoïdes comprenant des combinaisons hétérogènes de constituants épithéliaux et mésenchymateux, et leurs procédés de préparation par dissociation et recombinaison des constituants épithéliaux et mésenchymateux de différentes sources. Ces constituants épithéliaux et mésenchymateux peuvent être dérivés d'un type de cellules, ou d'organoïdes, identiques ou différents. Ces compositions d'organoïdes peuvent présenter des propriétés avantageuses, par exemple, une prise de greffe in vivo améliorée.</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBDzD3J39PP3dFEIcnX293Xy9HMM8fT342FgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgZGRgbmRqamxo6GxsSpAgA6ViAi</recordid><startdate>20220407</startdate><enddate>20220407</enddate><creator>BROWN, Nicole</creator><creator>SINGH, Akaljot</creator><creator>SUNDARAM, Nambirajan</creator><creator>HELMRATH, Michael</creator><creator>VALES, Simon</creator><scope>EVB</scope></search><sort><creationdate>20220407</creationdate><title>ORGANOID RECOMBINATION</title><author>BROWN, Nicole ; SINGH, Akaljot ; SUNDARAM, Nambirajan ; HELMRATH, Michael ; VALES, Simon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022072553A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>BROWN, Nicole</creatorcontrib><creatorcontrib>SINGH, Akaljot</creatorcontrib><creatorcontrib>SUNDARAM, Nambirajan</creatorcontrib><creatorcontrib>HELMRATH, Michael</creatorcontrib><creatorcontrib>VALES, Simon</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BROWN, Nicole</au><au>SINGH, Akaljot</au><au>SUNDARAM, Nambirajan</au><au>HELMRATH, Michael</au><au>VALES, Simon</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ORGANOID RECOMBINATION</title><date>2022-04-07</date><risdate>2022</risdate><abstract>Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be derived from the same or different cell type or organoid type. These organoid compositions may exhibit advantageous properties, for example, enhanced in vivo engraftment.
Sont divulguées ici des compositions d'organoïdes comprenant des combinaisons hétérogènes de constituants épithéliaux et mésenchymateux, et leurs procédés de préparation par dissociation et recombinaison des constituants épithéliaux et mésenchymateux de différentes sources. Ces constituants épithéliaux et mésenchymateux peuvent être dérivés d'un type de cellules, ou d'organoïdes, identiques ou différents. Ces compositions d'organoïdes peuvent présenter des propriétés avantageuses, par exemple, une prise de greffe in vivo améliorée.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | ORGANOID RECOMBINATION |
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