A PHARMACEUTICAL COMPOSITION COMPRISING FENOFIBRATE PARTICLES WITH IMPROVED BIOAVAILABILITY
Provided is a pharmaceutical composition comprising finely pulverized fenofibrate particles, a surfactant, and a hydrophilic polymer. According to the present invention, by selecting an appropriate fenofibrate particle size and an appropriate hydrophilic polymer content, it is possible to provide a...
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| creator | LEE, Tae Won CHO, Sung Jo MIN, Hyun Ki LEE, Kyu Ho HONG, Eui Seok |
| description | Provided is a pharmaceutical composition comprising finely pulverized fenofibrate particles, a surfactant, and a hydrophilic polymer. According to the present invention, by selecting an appropriate fenofibrate particle size and an appropriate hydrophilic polymer content, it is possible to provide a fenofibrate composition having bioavailability independent of dietary intake although using micrometer-sized fenofibrate particles.
L'invention concerne une composition pharmaceutique comprenant des particules de fénofibrate finement pulvérisées, un tensioactif et un polymère hydrophile. Selon la présente invention, par la sélection d'une taille de particule de fénofibrate et d'une teneur en polymère hydrophile appropriées, il est possible d'obtenir une composition de fénofibrate ayant une biodisponibilité indépendante du régime alimentaire malgré l'utilisation de particules de fénofibrate de taille micrométrique. |
| format | Patent |
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L'invention concerne une composition pharmaceutique comprenant des particules de fénofibrate finement pulvérisées, un tensioactif et un polymère hydrophile. Selon la présente invention, par la sélection d'une taille de particule de fénofibrate et d'une teneur en polymère hydrophile appropriées, il est possible d'obtenir une composition de fénofibrate ayant une biodisponibilité indépendante du régime alimentaire malgré l'utilisation de particules de fénofibrate de taille micrométrique.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220407&DB=EPODOC&CC=WO&NR=2022071768A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220407&DB=EPODOC&CC=WO&NR=2022071768A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE, Tae Won</creatorcontrib><creatorcontrib>CHO, Sung Jo</creatorcontrib><creatorcontrib>MIN, Hyun Ki</creatorcontrib><creatorcontrib>LEE, Kyu Ho</creatorcontrib><creatorcontrib>HONG, Eui Seok</creatorcontrib><title>A PHARMACEUTICAL COMPOSITION COMPRISING FENOFIBRATE PARTICLES WITH IMPROVED BIOAVAILABILITY</title><description>Provided is a pharmaceutical composition comprising finely pulverized fenofibrate particles, a surfactant, and a hydrophilic polymer. According to the present invention, by selecting an appropriate fenofibrate particle size and an appropriate hydrophilic polymer content, it is possible to provide a fenofibrate composition having bioavailability independent of dietary intake although using micrometer-sized fenofibrate particles.
L'invention concerne une composition pharmaceutique comprenant des particules de fénofibrate finement pulvérisées, un tensioactif et un polymère hydrophile. Selon la présente invention, par la sélection d'une taille de particule de fénofibrate et d'une teneur en polymère hydrophile appropriées, il est possible d'obtenir une composition de fénofibrate ayant une biodisponibilité indépendante du régime alimentaire malgré l'utilisation de particules de fénofibrate de taille micrométrique.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEuDqK-w4Gz0EawXS8xsQdprqSxRRxKkTiJFur7YxEfwOn_h2-ZXBHqEn2FSp8DKbSguKq5oUDsvu-pIXcCox0bkh6Dhhr9bK1uoKNQAs2IW30ESYwtkkVJlsJlnSzuw2OKm19XydbooMpdHF99nMbhFp_x3XcsUiHSPMsPBWb7_9QHksQzjg</recordid><startdate>20220407</startdate><enddate>20220407</enddate><creator>LEE, Tae Won</creator><creator>CHO, Sung Jo</creator><creator>MIN, Hyun Ki</creator><creator>LEE, Kyu Ho</creator><creator>HONG, Eui Seok</creator><scope>EVB</scope></search><sort><creationdate>20220407</creationdate><title>A PHARMACEUTICAL COMPOSITION COMPRISING FENOFIBRATE PARTICLES WITH IMPROVED BIOAVAILABILITY</title><author>LEE, Tae Won ; CHO, Sung Jo ; MIN, Hyun Ki ; LEE, Kyu Ho ; HONG, Eui Seok</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022071768A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE, Tae Won</creatorcontrib><creatorcontrib>CHO, Sung Jo</creatorcontrib><creatorcontrib>MIN, Hyun Ki</creatorcontrib><creatorcontrib>LEE, Kyu Ho</creatorcontrib><creatorcontrib>HONG, Eui Seok</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE, Tae Won</au><au>CHO, Sung Jo</au><au>MIN, Hyun Ki</au><au>LEE, Kyu Ho</au><au>HONG, Eui Seok</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A PHARMACEUTICAL COMPOSITION COMPRISING FENOFIBRATE PARTICLES WITH IMPROVED BIOAVAILABILITY</title><date>2022-04-07</date><risdate>2022</risdate><abstract>Provided is a pharmaceutical composition comprising finely pulverized fenofibrate particles, a surfactant, and a hydrophilic polymer. According to the present invention, by selecting an appropriate fenofibrate particle size and an appropriate hydrophilic polymer content, it is possible to provide a fenofibrate composition having bioavailability independent of dietary intake although using micrometer-sized fenofibrate particles.
L'invention concerne une composition pharmaceutique comprenant des particules de fénofibrate finement pulvérisées, un tensioactif et un polymère hydrophile. Selon la présente invention, par la sélection d'une taille de particule de fénofibrate et d'une teneur en polymère hydrophile appropriées, il est possible d'obtenir une composition de fénofibrate ayant une biodisponibilité indépendante du régime alimentaire malgré l'utilisation de particules de fénofibrate de taille micrométrique.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | A PHARMACEUTICAL COMPOSITION COMPRISING FENOFIBRATE PARTICLES WITH IMPROVED BIOAVAILABILITY |
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