MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE
Provided are multi- specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gpl20. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection. L'invention concerne des moléc...
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| creator | BACA, Manuel GOLDSMITH, Joshua BLAIR, Wade S STEPHENSON, Heather T PAN, YenRu THOMSEN, Nathan D HUNG, Magdeleine S NAGEL, Mark CLANCY, Sheila B KANWAR, Manu CARR, Brian A MOLDT, Brian PACE, Craig S |
| description | Provided are multi- specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gpl20. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
L'invention concerne des molécules de liaison à un antigène multi-spécifiques, comprenant des anticorps bispécifiques, qui se lient à CD3 et à un antigène du VIH, y compris à la protéine d'enveloppe du VIH gpl20. L'invention concerne également des méthodes d'utilisation de ces molécules de liaison à un antigène pour traiter ou prévenir toute infection par le VIH. |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE |
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