S100 PROTEINS AS NOVEL THERAPEUTIC TARGETS IN MYELOPROLIFERATIVE NEOPLASMS
The current invention pertains an inhibitor of an S100 protein, preferably an inhibitor of an S100A8 or S100A9 protein, for the prevention or treatment of a myeloproliferative neoplasm. In particular, the invention pertains to an inhibitor of an S100A8 orS100A9 protein, for the prevention ortreatmen...
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creator | SCHNEIDER-KRAMANN, Rebekka Katharina Marita |
description | The current invention pertains an inhibitor of an S100 protein, preferably an inhibitor of an S100A8 or S100A9 protein, for the prevention or treatment of a myeloproliferative neoplasm. In particular, the invention pertains to an inhibitor of an S100A8 orS100A9 protein, for the prevention ortreatment of primary myelofibrosis. The invention further pertains to an diagnostic method for identifying a subject suffering from a myeloproliferative neoplasm, comprising a step of detecting the presence of an S100 protein, preferably S100A8 or S100A9, in a biological sample.
La présente invention concerne un inhibiteur d'une protéine S100, de préférence un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement d'une tumeur myéloproliférative. En particulier, l'invention concerne un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement de la myélofibrose primitive. L'invention concerne en outre une méthode de diagnostic permettant d'identifier un sujet souffrant d'une tumeur myéloproliférative, comprenant une étape de détection de la présence d'une protéine S100, de préférence S100A8 ou S100A9, dans un échantillon biologique. |
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La présente invention concerne un inhibiteur d'une protéine S100, de préférence un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement d'une tumeur myéloproliférative. En particulier, l'invention concerne un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement de la myélofibrose primitive. L'invention concerne en outre une méthode de diagnostic permettant d'identifier un sujet souffrant d'une tumeur myéloproliférative, comprenant une étape de détection de la présence d'une protéine S100, de préférence S100A8 ou S100A9, dans un échantillon biologique.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220127&DB=EPODOC&CC=WO&NR=2022018240A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220127&DB=EPODOC&CC=WO&NR=2022018240A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SCHNEIDER-KRAMANN, Rebekka Katharina Marita</creatorcontrib><title>S100 PROTEINS AS NOVEL THERAPEUTIC TARGETS IN MYELOPROLIFERATIVE NEOPLASMS</title><description>The current invention pertains an inhibitor of an S100 protein, preferably an inhibitor of an S100A8 or S100A9 protein, for the prevention or treatment of a myeloproliferative neoplasm. In particular, the invention pertains to an inhibitor of an S100A8 orS100A9 protein, for the prevention ortreatment of primary myelofibrosis. The invention further pertains to an diagnostic method for identifying a subject suffering from a myeloproliferative neoplasm, comprising a step of detecting the presence of an S100 protein, preferably S100A8 or S100A9, in a biological sample.
La présente invention concerne un inhibiteur d'une protéine S100, de préférence un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement d'une tumeur myéloproliférative. En particulier, l'invention concerne un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement de la myélofibrose primitive. L'invention concerne en outre une méthode de diagnostic permettant d'identifier un sujet souffrant d'une tumeur myéloproliférative, comprenant une étape de détection de la présence d'une protéine S100, de préférence S100A8 ou S100A9, dans un échantillon biologique.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAKNjQwUAgI8g9x9fQLVnAMVvDzD3P1UQjxcA1yDHANDfF0VghxDHJ3DQlW8PRT8I109fEHqvbxdAPKh3iGuSr4ufoH-DgG-wbzMLCmJeYUp_JCaW4GZTfXEGcP3dSC_PjU4oLE5NS81JL4cH8jAyMjA0MLIxMDR0Nj4lQBACLqLn4</recordid><startdate>20220127</startdate><enddate>20220127</enddate><creator>SCHNEIDER-KRAMANN, Rebekka Katharina Marita</creator><scope>EVB</scope></search><sort><creationdate>20220127</creationdate><title>S100 PROTEINS AS NOVEL THERAPEUTIC TARGETS IN MYELOPROLIFERATIVE NEOPLASMS</title><author>SCHNEIDER-KRAMANN, Rebekka Katharina Marita</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022018240A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SCHNEIDER-KRAMANN, Rebekka Katharina Marita</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SCHNEIDER-KRAMANN, Rebekka Katharina Marita</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>S100 PROTEINS AS NOVEL THERAPEUTIC TARGETS IN MYELOPROLIFERATIVE NEOPLASMS</title><date>2022-01-27</date><risdate>2022</risdate><abstract>The current invention pertains an inhibitor of an S100 protein, preferably an inhibitor of an S100A8 or S100A9 protein, for the prevention or treatment of a myeloproliferative neoplasm. In particular, the invention pertains to an inhibitor of an S100A8 orS100A9 protein, for the prevention ortreatment of primary myelofibrosis. The invention further pertains to an diagnostic method for identifying a subject suffering from a myeloproliferative neoplasm, comprising a step of detecting the presence of an S100 protein, preferably S100A8 or S100A9, in a biological sample.
La présente invention concerne un inhibiteur d'une protéine S100, de préférence un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement d'une tumeur myéloproliférative. En particulier, l'invention concerne un inhibiteur d'une protéine S100A8 ou S100A9, destiné à la prévention ou au traitement de la myélofibrose primitive. L'invention concerne en outre une méthode de diagnostic permettant d'identifier un sujet souffrant d'une tumeur myéloproliférative, comprenant une étape de détection de la présence d'une protéine S100, de préférence S100A8 ou S100A9, dans un échantillon biologique.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | S100 PROTEINS AS NOVEL THERAPEUTIC TARGETS IN MYELOPROLIFERATIVE NEOPLASMS |
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