DIAGNOSISIN VITROOF MULTIPLE SCLEROSIS

Multiple sclerosis (MS) is a demyelinating neurodegenerative disease that affects approximately 2.3 million people worldwide. To date, there is no single test available that can definitely and indisputably confirm the diagnosis of MS, just as there are no diagnostic or predictive bio-markers for the...

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Hauptverfasser: GRANDI, Nicole, TRAMONTANO, Enzo, PISANO, Maria Paola
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TRAMONTANO, Enzo
PISANO, Maria Paola
description Multiple sclerosis (MS) is a demyelinating neurodegenerative disease that affects approximately 2.3 million people worldwide. To date, there is no single test available that can definitely and indisputably confirm the diagnosis of MS, just as there are no diagnostic or predictive bio-markers for the disease. The present invention relates to a new method for the in vitro diagnosis of multiple sclerosis. In particular, the invention has as its object the analysis of the expression levels of specific transcripts deriving from Human Endogenous Retroviruses (HERV). La sclérose en plaques (SEP) est une maladie neurodégénérative démyélinisante qui affecte environ 2,3 millions de personnes dans le monde. A ce jour, il n'y a pas d'essai unique disponible qui peut confirmer de manière sûre et indiscutable le diagnostic de SEP, simplement étant donné qu'il n'y a pas de marqueurs biologiques diagnostiques ou prédictifs pour la maladie. La présente invention concerne un nouveau procédé de diagnostic in vitro de la sclérose en plaques. En particulier, l'invention a pour objet l'analyse des niveaux d'expression de transcrits spécifiques issus de rétrovirus endogènes humains (HERV).
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title DIAGNOSISIN VITROOF MULTIPLE SCLEROSIS
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