LIVE ATTENUATED STRAINS OF FOOT AND MOUTH DISEASE MODIFIED BY DEOPTIMIZATION AND USES THEREOF

The present disclosure describes deoptimized foot and mouth viruses and their use for prophylactic and therapeutic treatment of mammalian subjects. The recombinant viruses provided herein include alterations in several genomic regions as well as Differentiating Infected from Vaccinated Animals (DIVA...

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Hauptverfasser: DIAZ-SAN SEGUNDO, Fayna C, COLEMAN, John R, RIEDER, Aida E, MEDINA, Gisselle N, MUELLER, Steffen, KLOC, Anna, DE LOS SANTOS, Teresa B
Format: Patent
Sprache:eng ; fre
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