AN APPARATUS COMPRISING MICROFLUIDIC PROTEIN-BASED SENSORS AND METHODS OF USING SAME

An automatic and continuous glucose monitoring apparatus and method of using same based on binding proteins. The apparatus integrates an aseptic sampling technique, a specially modified chromatography column to hold immobilized binding protein, and a microfluorometer into a compact portable device....

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Hauptverfasser: RAO, Govind, KOSTOV, Yordan, HASAN, Hasibul, WONG, Lynn, ANDAR, Abhay, CROUCHER, Leah Tolosa, GE, Xudong, BROWN, Sheniqua
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creator RAO, Govind
KOSTOV, Yordan
HASAN, Hasibul
WONG, Lynn
ANDAR, Abhay
CROUCHER, Leah Tolosa
GE, Xudong
BROWN, Sheniqua
description An automatic and continuous glucose monitoring apparatus and method of using same based on binding proteins. The apparatus integrates an aseptic sampling technique, a specially modified chromatography column to hold immobilized binding protein, and a microfluorometer into a compact portable device. The apparatus permits the measurement of a very wide range of concentrations - from a few micromolar to several hundreds of millimolar of glucose. L'invention concerne un appareil de surveillance de glucose automatique et continu et un procédé d'utilisation de celui-ci sur la base de protéines de liaison. L'appareil intègre une technique d'échantillonnage aseptique, une colonne de chromatographie spécialement modifiée pour contenir une protéine de liaison immobilisée, et un microfluoromètre dans un dispositif portable compact. L'appareil permet la mesure d'une très large gamme de concentrations de quelques micromolaires à plusieurs centaines de millimolaires de glucose.
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subjects APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
SPIRITS
TESTING
VINEGAR
WINE
title AN APPARATUS COMPRISING MICROFLUIDIC PROTEIN-BASED SENSORS AND METHODS OF USING SAME
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