CEFTRIAXONE COMPOSITIONS WITH MAGNESIUM COMPONENT

A liquid pharmaceutical composition comprising ceftriaxone or a pharmaceutical acceptable salt or derivative thereof and at least one magnesium salt, magnesium oxide, and/or magnesium hydroxide is provided. Also provided are a method for treating bacterial infections in a subject by administering an...

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Hauptverfasser: ZRNC, Katarina, JASPRICA, Ivona, HORVAT, Peter
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Sprache:eng ; fre
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creator ZRNC, Katarina
JASPRICA, Ivona
HORVAT, Peter
description A liquid pharmaceutical composition comprising ceftriaxone or a pharmaceutical acceptable salt or derivative thereof and at least one magnesium salt, magnesium oxide, and/or magnesium hydroxide is provided. Also provided are a method for treating bacterial infections in a subject by administering any of the compositions described herein, as well as a method for stabilizing ceftriaxone in a liquid pharmaceutical composition by mixing ceftriaxone and at least one magnesium salt, magnesium oxide, and/or magnesium hydroxide. L'invention concerne une composition pharmaceutique liquide comprenant du ceftriaxone ou un sel pharmaceutiquement acceptable ou un dérivé de celui-ci et au moins un sel de magnésium, de l'oxyde de magnésium et/ou de l'hydroxyde de magnésium. L'invention concerne également une méthode de traitement d'infections bactériennes chez un sujet par l'administration de l'une quelconque desdites compositions, ainsi qu'un procédé de stabilisation de ceftriaxone dans une composition pharmaceutique liquide par mélange de ceftriaxone et d'au moins un sel de magnésium, d'oxyde de magnésium et/ou d'hydroxyde de magnésium.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CEFTRIAXONE COMPOSITIONS WITH MAGNESIUM COMPONENT
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