ROSMARINIC ACID DERIVATIVE, ROSMARINIC ACID-DERIVED PARTICLES, AND COMPOSITION COMPRISING SAME FOR TREATING INFLAMMATORY DISEASE

The present invention relates to a rosmarinic acid derivative, rosmarinic acid-derived particles, and a composition comprising same for treating an inflammatory disease. The use of the rosmarinic acid derivative and rosmarinic acid-derived particles of the present invention can enable the utilizatio...

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Bibliographische Detailangaben
Hauptverfasser: JON, Sang Yong, JUNG, Wonsik, CHUNG, Chan Ho, RAHMAN, Afia Tasnim
Format: Patent
Sprache:eng ; fre ; kor
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Zusammenfassung:The present invention relates to a rosmarinic acid derivative, rosmarinic acid-derived particles, and a composition comprising same for treating an inflammatory disease. The use of the rosmarinic acid derivative and rosmarinic acid-derived particles of the present invention can enable the utilization, for a pharmaceutical purpose, of rosmarinic acid that has been restricted in the utilization due to low solubility in water and low bioavailability. La présente invention concerne un dérivé d'acide rosmarinique, des particules dérivées de l'acide rosmarinique, et une composition les comprenant aux fins du traitement d'une maladie inflammatoire. L'utilisation du dérivé d'acide rosmarinique et des particules dérivées de l'acide rosmarinique de la présente invention peut permettre l'utilisation, à des fins pharmaceutiques, de l'acide rosmarinique qui a été restreint dans l'utilisation en raison d'une faible solubilité dans l'eau et d'une faible biodisponibilité. 본 발명은 로즈마린산 유도체, 로즈마린산-유래 입자 및 이를 포함하는 염증성 질환 치료용 조성물에 관한 것이다. 본 발명의 로즈마린산 유도체 및 로즈마린산-유래 입자를 이용하는 경우, 낮은 수용성과 낮은 생체 이용률로 인해 활용이 제한되었던 로즈마린산을 의약 용도로 활용할 수 있다.