PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)

Pyrrolo[2,3-f]indazole and 2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-l,3(7),5,8,ll-pentaene derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD) L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodé...

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Hauptverfasser: HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, JOHNSON, JR, HURLEY, Dennis James, BOUCHER, Diane Marie, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, FIMOGNARI, JR, GREY, JR, THOMSON, Stephen A, FANNING, Lev T, SWETT, Rebecca Jane, GIROUX, Simon, NUHANT, Philippe Marcel
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creator HALL, Amy B
COTTRELL, Kevin Michael
BRODNEY, Michael Aaron
BOYD, Michael John
ZAKY, Mariam
GARCIA BARRANTES, Pedro Manuel
JOHNSON, JR
HURLEY, Dennis James
BOUCHER, Diane Marie
MAXWELL, John Patrick
XU, Jinwang
DAMAGNEZ, Veronique
KESAVAN, Sarathy
JONES, Peter
TAPLEY, Timothy Lewis
FIMOGNARI, JR
GREY, JR
THOMSON, Stephen A
FANNING, Lev T
SWETT, Rebecca Jane
GIROUX, Simon
NUHANT, Philippe Marcel
description Pyrrolo[2,3-f]indazole and 2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-l,3(7),5,8,ll-pentaene derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD) L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodéca-l,3(7),5,8,ll-pentaène en tant que modulateurs d'alpha-1-antitrypsine pour traiter une déficience en alpha-1-antitrypsine (AATD).
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
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