PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
Pyrrolo[2,3-f]indazole and 2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-l,3(7),5,8,ll-pentaene derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD) L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodé...
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creator | HALL, Amy B COTTRELL, Kevin Michael BRODNEY, Michael Aaron BOYD, Michael John ZAKY, Mariam GARCIA BARRANTES, Pedro Manuel JOHNSON, JR HURLEY, Dennis James BOUCHER, Diane Marie MAXWELL, John Patrick XU, Jinwang DAMAGNEZ, Veronique KESAVAN, Sarathy JONES, Peter TAPLEY, Timothy Lewis FIMOGNARI, JR GREY, JR THOMSON, Stephen A FANNING, Lev T SWETT, Rebecca Jane GIROUX, Simon NUHANT, Philippe Marcel |
description | Pyrrolo[2,3-f]indazole and 2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-l,3(7),5,8,ll-pentaene derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD)
L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodéca-l,3(7),5,8,ll-pentaène en tant que modulateurs d'alpha-1-antitrypsine pour traiter une déficience en alpha-1-antitrypsine (AATD). |
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L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodéca-l,3(7),5,8,ll-pentaène en tant que modulateurs d'alpha-1-antitrypsine pour traiter une déficience en alpha-1-antitrypsine (AATD).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211007&DB=EPODOC&CC=WO&NR=2021203010A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211007&DB=EPODOC&CC=WO&NR=2021203010A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HALL, Amy B</creatorcontrib><creatorcontrib>COTTRELL, Kevin Michael</creatorcontrib><creatorcontrib>BRODNEY, Michael Aaron</creatorcontrib><creatorcontrib>BOYD, Michael John</creatorcontrib><creatorcontrib>ZAKY, Mariam</creatorcontrib><creatorcontrib>GARCIA BARRANTES, Pedro Manuel</creatorcontrib><creatorcontrib>JOHNSON, JR</creatorcontrib><creatorcontrib>HURLEY, Dennis James</creatorcontrib><creatorcontrib>BOUCHER, Diane Marie</creatorcontrib><creatorcontrib>MAXWELL, John Patrick</creatorcontrib><creatorcontrib>XU, Jinwang</creatorcontrib><creatorcontrib>DAMAGNEZ, Veronique</creatorcontrib><creatorcontrib>KESAVAN, Sarathy</creatorcontrib><creatorcontrib>JONES, Peter</creatorcontrib><creatorcontrib>TAPLEY, Timothy Lewis</creatorcontrib><creatorcontrib>FIMOGNARI, JR</creatorcontrib><creatorcontrib>GREY, JR</creatorcontrib><creatorcontrib>THOMSON, Stephen A</creatorcontrib><creatorcontrib>FANNING, Lev T</creatorcontrib><creatorcontrib>SWETT, Rebecca Jane</creatorcontrib><creatorcontrib>GIROUX, Simon</creatorcontrib><creatorcontrib>NUHANT, Philippe Marcel</creatorcontrib><title>PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)</title><description>Pyrrolo[2,3-f]indazole and 2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-l,3(7),5,8,ll-pentaene derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD)
L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodéca-l,3(7),5,8,ll-pentaène en tant que modulateurs d'alpha-1-antitrypsine pour traiter une déficience en alpha-1-antitrypsine (AATD).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNys1KAzEUQOHZuJDqOwS6aSEZ8mMZt5fkjg2MyXDnWplKKUXiSrRQX893MwuXLoQDZ_NdN9_jTJSH_GKlU_0hpgD7PKCAFISVd3IjjVaMTLAHpuhnX23Xula32snuEHJAD8pIt-rWVd9LY9SIiQETioAUd8Bxh5OA2jBuq1WQODLN4xSTeMzhaQDONIk-k2DC6tPDnzZgH33E5GexAuCwvmmu3k7vl3L7-0Wz7JH9VpXz57FczqfX8lG-js_ZamusdtpoMO5_6gcqdUuB</recordid><startdate>20211007</startdate><enddate>20211007</enddate><creator>HALL, Amy B</creator><creator>COTTRELL, Kevin Michael</creator><creator>BRODNEY, Michael Aaron</creator><creator>BOYD, Michael John</creator><creator>ZAKY, Mariam</creator><creator>GARCIA BARRANTES, Pedro Manuel</creator><creator>JOHNSON, JR</creator><creator>HURLEY, Dennis James</creator><creator>BOUCHER, Diane Marie</creator><creator>MAXWELL, John Patrick</creator><creator>XU, Jinwang</creator><creator>DAMAGNEZ, Veronique</creator><creator>KESAVAN, Sarathy</creator><creator>JONES, Peter</creator><creator>TAPLEY, Timothy Lewis</creator><creator>FIMOGNARI, JR</creator><creator>GREY, JR</creator><creator>THOMSON, Stephen A</creator><creator>FANNING, Lev T</creator><creator>SWETT, Rebecca Jane</creator><creator>GIROUX, Simon</creator><creator>NUHANT, Philippe Marcel</creator><scope>EVB</scope></search><sort><creationdate>20211007</creationdate><title>PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)</title><author>HALL, Amy B ; COTTRELL, Kevin Michael ; BRODNEY, Michael Aaron ; BOYD, Michael John ; ZAKY, Mariam ; GARCIA BARRANTES, Pedro Manuel ; JOHNSON, JR ; HURLEY, Dennis James ; BOUCHER, Diane Marie ; MAXWELL, John Patrick ; XU, Jinwang ; DAMAGNEZ, Veronique ; KESAVAN, Sarathy ; JONES, Peter ; TAPLEY, Timothy Lewis ; FIMOGNARI, JR ; GREY, JR ; THOMSON, Stephen A ; FANNING, Lev T ; SWETT, Rebecca Jane ; GIROUX, Simon ; NUHANT, Philippe Marcel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2021203010A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HALL, Amy B</creatorcontrib><creatorcontrib>COTTRELL, Kevin Michael</creatorcontrib><creatorcontrib>BRODNEY, Michael Aaron</creatorcontrib><creatorcontrib>BOYD, Michael John</creatorcontrib><creatorcontrib>ZAKY, Mariam</creatorcontrib><creatorcontrib>GARCIA BARRANTES, Pedro Manuel</creatorcontrib><creatorcontrib>JOHNSON, JR</creatorcontrib><creatorcontrib>HURLEY, Dennis James</creatorcontrib><creatorcontrib>BOUCHER, Diane Marie</creatorcontrib><creatorcontrib>MAXWELL, John Patrick</creatorcontrib><creatorcontrib>XU, Jinwang</creatorcontrib><creatorcontrib>DAMAGNEZ, Veronique</creatorcontrib><creatorcontrib>KESAVAN, Sarathy</creatorcontrib><creatorcontrib>JONES, Peter</creatorcontrib><creatorcontrib>TAPLEY, Timothy Lewis</creatorcontrib><creatorcontrib>FIMOGNARI, JR</creatorcontrib><creatorcontrib>GREY, JR</creatorcontrib><creatorcontrib>THOMSON, Stephen A</creatorcontrib><creatorcontrib>FANNING, Lev T</creatorcontrib><creatorcontrib>SWETT, Rebecca Jane</creatorcontrib><creatorcontrib>GIROUX, Simon</creatorcontrib><creatorcontrib>NUHANT, Philippe Marcel</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HALL, Amy B</au><au>COTTRELL, Kevin Michael</au><au>BRODNEY, Michael Aaron</au><au>BOYD, Michael John</au><au>ZAKY, Mariam</au><au>GARCIA BARRANTES, Pedro Manuel</au><au>JOHNSON, JR</au><au>HURLEY, Dennis James</au><au>BOUCHER, Diane Marie</au><au>MAXWELL, John Patrick</au><au>XU, Jinwang</au><au>DAMAGNEZ, Veronique</au><au>KESAVAN, Sarathy</au><au>JONES, Peter</au><au>TAPLEY, Timothy Lewis</au><au>FIMOGNARI, JR</au><au>GREY, JR</au><au>THOMSON, Stephen A</au><au>FANNING, Lev T</au><au>SWETT, Rebecca Jane</au><au>GIROUX, Simon</au><au>NUHANT, Philippe Marcel</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)</title><date>2021-10-07</date><risdate>2021</risdate><abstract>Pyrrolo[2,3-f]indazole and 2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-l,3(7),5,8,ll-pentaene derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD)
L'invention concerne des dérivés de pyrrolo[2,3-f]indazole et de 2,4,5,10-tétrazatricyclo[7.3.0.03,7]dodéca-l,3(7),5,8,ll-pentaène en tant que modulateurs d'alpha-1-antitrypsine pour traiter une déficience en alpha-1-antitrypsine (AATD).</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) |
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