INTRA-GENOMIC HOMOLOGOUS RECOMBINATION
Compositions and methods are provided for an inducible, high efficiency intra-genomic homologous recombination (IGHR) system in plants, that can be used for non-chimeric, heritable gene targeting. The advantage of IGHR approach to targeted integration is that every cell contains donor DNA and nuclea...
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| creator | WU, Xinli Emily CHO, Hyeon-Je GORDON-KAMM, William James SVITASHEV, Sergei ARLING, Maren L BARONE, Pierluigi LENDERTS, Brian ANAND, Ajith LOWE, Keith S KUMAR, Sandeep |
| description | Compositions and methods are provided for an inducible, high efficiency intra-genomic homologous recombination (IGHR) system in plants, that can be used for non-chimeric, heritable gene targeting. The advantage of IGHR approach to targeted integration is that every cell contains donor DNA and nuclease-encoding sequences, so that there are many potentially homology-directed targeting events that can occur during plant development.
L'invention concerne des compositions et des procédés pour un système de recombinaison homologue intragénomique inductible (IGHR) à haut rendement chez la plante, qui peut être utilisé pour le ciblage de gènes héréditaires non chimériques. L'avantage d'une approche d'IGHR pour une intégration ciblée est que chaque cellule contient de l'ADN donneur et des séquences codant pour une nucléase, de sorte qu'il existe de nombreux événements de ciblage dirigés potentiellement par homologie qui peuvent se produire pendant le développement de la plante. |
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L'invention concerne des compositions et des procédés pour un système de recombinaison homologue intragénomique inductible (IGHR) à haut rendement chez la plante, qui peut être utilisé pour le ciblage de gènes héréditaires non chimériques. L'avantage d'une approche d'IGHR pour une intégration ciblée est que chaque cellule contient de l'ADN donneur et des séquences codant pour une nucléase, de sorte qu'il existe de nombreux événements de ciblage dirigés potentiellement par homologie qui peuvent se produire pendant le développement de la plante.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | INTRA-GENOMIC HOMOLOGOUS RECOMBINATION |
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