METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT

Disclosed are pharmaceutical combinations and methods of treating a clinical condition, e.g., AML, by administering to a subject a pharmaceutical combination comprising a DHODH inhibitor and an anti-CD38 therapeutic agent such as a anti-CD38 antibody. The pharmaceutical combination can further compr...

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Hauptverfasser: BYRD, John C, JOHNSON, Mariah L, HERTLEIN, Erin, BENNETT, Chad E, VIBHUTE, Sandip Madhukar, GOODWIN, Thomas E, TRIDANDAPANI, Susheela, ELGAMAL, Ola A
Format: Patent
Sprache:eng ; fre
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