COMPOSITIONS AND METHODS OF TREATMENT

COMPOSITIONS AND METHODS OF TREATMENT

Pharmaceutical compositions are provided containing tert-butyI-{[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]methyl}piperazine-1-carboxylate or a pharmaceutically acceptable salt thereof, more particularly to certain orally deliverable immediate release solid pharmaceutical compositio...

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Hauptverfasser: MOE, Derek, LEVESQUE, Barrett, MARTINEZ, Nathaniel Santos
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Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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LEVESQUE, Barrett
MARTINEZ, Nathaniel Santos
description Pharmaceutical compositions are provided containing tert-butyI-{[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]methyl}piperazine-1-carboxylate or a pharmaceutically acceptable salt thereof, more particularly to certain orally deliverable immediate release solid pharmaceutical compositions containing a pharmaceutically acceptable salt of tert-butyI-{[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]methyl}piperazine-1-carboxylate and orally deliverable delayed release solid pharmaceutical compositions containing tert-butyI-{[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]methyl}piperazine-1-carboxylate or a pharmaceutically acceptable salt of. Also provided are methods and uses related to said compositions, as well as processes for the preparation of said compositions, and certain dosage regimens for the administration thereof. L'invention concerne des compositions pharmaceutiques contenant du {[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]méthyl}pipérazine-1-carboxylate de tert-butyIe ou un sel pharmaceutiquement acceptable de celui-ci, plus particulièrement, certaines compositions pharmaceutiques solides à libération immédiate pouvant être administrées par voie orale contenant un sel pharmaceutiquement acceptable du {[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]méthyl}pipérazine-1-carboxylate de tert-butyIe et des compositions pharmaceutiques solides à libération retardée pouvant être administrées par voie orale contenant du {[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]méthyl}pipérazine-1-carboxylate de tert-butyIe ou un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne également des méthodes et des utilisations associées auxdites compositions, ainsi que des procédés de préparation desdites compositions, et certains régimes posologiques pour l'administration de celles-ci.
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Also provided are methods and uses related to said compositions, as well as processes for the preparation of said compositions, and certain dosage regimens for the administration thereof. L'invention concerne des compositions pharmaceutiques contenant du {[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]méthyl}pipérazine-1-carboxylate de tert-butyIe ou un sel pharmaceutiquement acceptable de celui-ci, plus particulièrement, certaines compositions pharmaceutiques solides à libération immédiate pouvant être administrées par voie orale contenant un sel pharmaceutiquement acceptable du {[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]méthyl}pipérazine-1-carboxylate de tert-butyIe et des compositions pharmaceutiques solides à libération retardée pouvant être administrées par voie orale contenant du {[1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl]méthyl}pipérazine-1-carboxylate de tert-butyIe ou un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne également des méthodes et des utilisations associées auxdites compositions, ainsi que des procédés de préparation desdites compositions, et certains régimes posologiques pour l'administration de celles-ci.</abstract><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSITIONS AND METHODS OF TREATMENT
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