COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASE

Disclosed are compositions and methods for treating a liver disease in a subject by increasing transport or retention of HNF4α, a transcriptional factor, into a nucleus of a hepatocyte in the subject. In some embodiments, the method comprises upregulating expression or function of one or more transc...

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Bibliographische Detailangaben
Hauptverfasser: TAKEISHI, Kazuki, SOTO GUTIERREZ, Alejandro, OSTROWSKA, Alina, GUZMAN LEPE, Jorge, FOX, Ira, FRAUNHOFFER NAVARRO, Nicolas, TAFALENG, Edgar Naoe, MICHALOPOULOS, George K, BELL, Aaron, HAINER, Sarah
Format: Patent
Sprache:eng ; fre
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