ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL

ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL

Aspects of the present application relate to process for the preparation of Omecamtiv mecarbil and salts thereof. Specific aspects relate to novel urea intermediate, preparative process thereof and its use in the preparation of Omecamtiv mecarbil and salts thereof. The improved process for the prepa...

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Bibliographische Detailangaben
Hauptverfasser: MOHAMMED, Azeezulla Baig, ORUGANTI, Srinivas, SAMPATH, Magesh, SEN, Saikat
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Aspects of the present application relate to process for the preparation of Omecamtiv mecarbil and salts thereof. Specific aspects relate to novel urea intermediate, preparative process thereof and its use in the preparation of Omecamtiv mecarbil and salts thereof. The improved process for the preparation of Omecamtiv mecarbil are industrially viable. Des aspects de la présente demande portent sur un procédé de préparation d'omécamtiv mécarbil et de sels de ce dernier. Des aspects spécifiques concernent un nouvel intermédiaire de l'urée, un procédé de préparation associé et son utilisation pour la préparation d'omécamtiv mécarbil et de sels de ce dernier. Le procédé amélioré de préparation d'omécamtiv mécarbil est viable à l'échelle industrielle.