HEMOGLOBIN-BASED NANOPARTICLES FOR OXYGEN DELIVERY

HEMOGLOBIN-BASED NANOPARTICLES FOR OXYGEN DELIVERY

Disclosed herein are oxygen transporting formulations, in particular those composed of hemoglobin-based nanoparticles, and their use and process of manufacture. These formulations are more uniform and monodisperse than prior hemoglobin-based oxygen carriers, such as polymeric hemoglobin. In addition...

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Hauptverfasser: PALMER, Andre, HICKEY, Richard
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Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator PALMER, Andre
HICKEY, Richard
description Disclosed herein are oxygen transporting formulations, in particular those composed of hemoglobin-based nanoparticles, and their use and process of manufacture. These formulations are more uniform and monodisperse than prior hemoglobin-based oxygen carriers, such as polymeric hemoglobin. In addition, these formulations provide higher hemoglobin encapsulation efficiencies and higher hemoglobin content that hemoglobin-containing vesicles. L'invention concerne des formulations de transport d'oxygène, en particulier celles composées de nanoparticules à base d'hémoglobine, et leur utilisation et leur procédé de fabrication. Ces formulations sont plus uniformes et monodispersées que les transporteurs d'oxygène à base d'hémoglobine de l'état de la technique, tels que l'hémoglobine polymérique. En outre, ces formulations offrent de meilleurs rendements d'encapsulation d'hémoglobine et une teneur en hémoglobine plus élevée que celle des vésicules contenant de l'hémoglobine.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title HEMOGLOBIN-BASED NANOPARTICLES FOR OXYGEN DELIVERY
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