ANTIBODIES AGAINST HUMAN TREM-1 AND USES THEREOF

ANTIBODIES AGAINST HUMAN TREM-1 AND USES THEREOF

Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TREM-1 signaling. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases. L'invention concerne d...

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Bibliographische Detailangaben
Hauptverfasser: RAKESTRAW, Ginger C, PASHINE, Achal M, TOTH, Joseph
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TREM-1 signaling. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases. L'invention concerne des anticorps, ou des parties de liaison à l'antigène de ceux-ci, qui se lient de manière spécifique et inhibent la signalisation TREM-1. L'invention concerne également des utilisations de ces anticorps, ou de parties de liaison à l'antigène de ceux-ci, dans des applications thérapeutiques, telles que le traitement de maladies auto-immunes.