PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS

The present disclosure provides methods for preparing (7?)-2-((2-amino-7- fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-l-ol or a salt thereof and related key intermediates. La présente invention concerne des procédés de préparation de (7)-2-((2-amino-7-fluoropyrido[3,2-d] pyrimidine-4-yl)...

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Hauptverfasser: VIEIRA, Tiago, ASSELIN, Sylvie M, REGENS, Christopher S, WEINSTEIN, Adam B, METOBO, Samuel E, PYUN, Hyung-Jung, LEW, Willard, ZHENG, Zehua, BACHRACH, Florence J, AMBROSI, Andrea, AKTOUDIANAKIS, Evangelos, CHIN, Gregory F, WANG, Xianghong, BADALOV, Pavel R, LATHROP, Stephen P, MACKMAN, Richard L, MISH, Michael R, MERIT, Jeffrey E, PRITCHETT, Beau P, WENDERSKI, Todd A
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creator VIEIRA, Tiago
ASSELIN, Sylvie M
REGENS, Christopher S
WEINSTEIN, Adam B
METOBO, Samuel E
PYUN, Hyung-Jung
LEW, Willard
ZHENG, Zehua
BACHRACH, Florence J
AMBROSI, Andrea
AKTOUDIANAKIS, Evangelos
CHIN, Gregory F
WANG, Xianghong
BADALOV, Pavel R
LATHROP, Stephen P
MACKMAN, Richard L
MISH, Michael R
MERIT, Jeffrey E
PRITCHETT, Beau P
WENDERSKI, Todd A
description The present disclosure provides methods for preparing (7?)-2-((2-amino-7- fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-l-ol or a salt thereof and related key intermediates. La présente invention concerne des procédés de préparation de (7)-2-((2-amino-7-fluoropyrido[3,2-d] pyrimidine-4-yl) amino)-2-méthylhexane-1-ol ou d'un sel de celui-ci et des intermédiaires clés associés.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS
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