COMPOSITION MODULATING BOTULINUM NEUROTOXIN EFFECT

The present invention relates to a method for modulating the effect of a botulinum neurotoxin composition, that is accelerating the onset of action and /or extending the duration of action and/or enhancing the intensity of action of a botulinum neurotoxin composition, comprising adding at least one...

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Hauptverfasser: HULO, Nicolas, MACHICOANE, Mickaël, LE DOUSSAL, Jean-Marc, CROS, Cécile
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creator HULO, Nicolas
MACHICOANE, Mickaël
LE DOUSSAL, Jean-Marc
CROS, Cécile
description The present invention relates to a method for modulating the effect of a botulinum neurotoxin composition, that is accelerating the onset of action and /or extending the duration of action and/or enhancing the intensity of action of a botulinum neurotoxin composition, comprising adding at least one postsynaptic inhibitor of cholinergic neuronal transmission to the botulinum neurotoxin composition. The invention also relates to compositions comprising at least one postsynaptic inhibitor of cholinergic neuronal transmission and a botulinum neurotoxin, and their uses for treating aesthetic or therapeutic conditions. La présente invention concerne un procédé de modulation de l'effet d'une composition de neurotoxine botulique, qui accélère l'apparition de l'action et/ou prolonge la durée de l'action et/ou améliore l'intensité de l'action d'une composition de neurotoxine botulique, comprenant l'ajout d'au moins un inhibiteur post-synaptique de la transmission neuronale cholinergique à la composition de neurotoxine botulique. L'invention concerne également des compositions comprenant au moins un inhibiteur post-synaptique de la transmission neuronale cholinergique et une neurotoxine botulique, et leurs utilisations pour le traitement d'états esthétiques ou thérapeutiques.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSITION MODULATING BOTULINUM NEUROTOXIN EFFECT
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