SORCS2 CRYSTAL STRUCTURE AND USES THEREOF
The present invention relates to a SorCS2 crystal structure, the atomic coordinates obtained by X-ray crystallography of same, and their use in molecular modelling. The invention further relates to methods of growing crystals of SorCS2. Furthermore, the invention relates to peptides capable of bindi...
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| creator | SKELDAL, Sune MADSEN, SØNDERGAARD ALMEIDA, Sergio Eduardo Costa SKOU THIRUP, Søren PEDERSEN, GLERUP VILSTRUP, Joachim Pold |
| description | The present invention relates to a SorCS2 crystal structure, the atomic coordinates obtained by X-ray crystallography of same, and their use in molecular modelling. The invention further relates to methods of growing crystals of SorCS2. Furthermore, the invention relates to peptides capable of binding to SorCS2, as well as their use as medicament, for example in the treatment of frontotemporal dementia.
La présente invention concerne une structure cristalline de SorCS2, ses coordonnées atomiques obtenues par cristallographie aux rayons X et leur utilisation dans la modélisation moléculaire. L'invention concerne en outre des procédés de croissance de cristaux de SorCS2. L'invention concerne par ailleurs des peptides capables de se lier à SorCS2, ainsi que leur utilisation comme médicament, par exemple dans le traitement de la démence frontotemporale. |
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La présente invention concerne une structure cristalline de SorCS2, ses coordonnées atomiques obtenues par cristallographie aux rayons X et leur utilisation dans la modélisation moléculaire. L'invention concerne en outre des procédés de croissance de cristaux de SorCS2. L'invention concerne par ailleurs des peptides capables de se lier à SorCS2, ainsi que leur utilisation comme médicament, par exemple dans le traitement de la démence frontotemporale.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210401&DB=EPODOC&CC=WO&NR=2020254683A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25555,76308</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210401&DB=EPODOC&CC=WO&NR=2020254683A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SKELDAL, Sune</creatorcontrib><creatorcontrib>MADSEN, SØNDERGAARD</creatorcontrib><creatorcontrib>ALMEIDA, Sergio Eduardo Costa</creatorcontrib><creatorcontrib>SKOU THIRUP, Søren</creatorcontrib><creatorcontrib>PEDERSEN, GLERUP</creatorcontrib><creatorcontrib>VILSTRUP, Joachim Pold</creatorcontrib><title>SORCS2 CRYSTAL STRUCTURE AND USES THEREOF</title><description>The present invention relates to a SorCS2 crystal structure, the atomic coordinates obtained by X-ray crystallography of same, and their use in molecular modelling. The invention further relates to methods of growing crystals of SorCS2. Furthermore, the invention relates to peptides capable of binding to SorCS2, as well as their use as medicament, for example in the treatment of frontotemporal dementia.
La présente invention concerne une structure cristalline de SorCS2, ses coordonnées atomiques obtenues par cristallographie aux rayons X et leur utilisation dans la modélisation moléculaire. L'invention concerne en outre des procédés de croissance de cristaux de SorCS2. L'invention concerne par ailleurs des peptides capables de se lier à SorCS2, ainsi que leur utilisation comme médicament, par exemple dans le traitement de la démence frontotemporale.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAM9g9yDjZScA6KDA5x9FEIDgkKdQ4JDXJVcPRzUQgNdg1WCPFwDXL1d-NhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGQGhqYmZh7GhsTJwqANBYJXM</recordid><startdate>20210401</startdate><enddate>20210401</enddate><creator>SKELDAL, Sune</creator><creator>MADSEN, SØNDERGAARD</creator><creator>ALMEIDA, Sergio Eduardo Costa</creator><creator>SKOU THIRUP, Søren</creator><creator>PEDERSEN, GLERUP</creator><creator>VILSTRUP, Joachim Pold</creator><scope>EVB</scope></search><sort><creationdate>20210401</creationdate><title>SORCS2 CRYSTAL STRUCTURE AND USES THEREOF</title><author>SKELDAL, Sune ; MADSEN, SØNDERGAARD ; ALMEIDA, Sergio Eduardo Costa ; SKOU THIRUP, Søren ; PEDERSEN, GLERUP ; VILSTRUP, Joachim Pold</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020254683A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SKELDAL, Sune</creatorcontrib><creatorcontrib>MADSEN, SØNDERGAARD</creatorcontrib><creatorcontrib>ALMEIDA, Sergio Eduardo Costa</creatorcontrib><creatorcontrib>SKOU THIRUP, Søren</creatorcontrib><creatorcontrib>PEDERSEN, GLERUP</creatorcontrib><creatorcontrib>VILSTRUP, Joachim Pold</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SKELDAL, Sune</au><au>MADSEN, SØNDERGAARD</au><au>ALMEIDA, Sergio Eduardo Costa</au><au>SKOU THIRUP, Søren</au><au>PEDERSEN, GLERUP</au><au>VILSTRUP, Joachim Pold</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SORCS2 CRYSTAL STRUCTURE AND USES THEREOF</title><date>2021-04-01</date><risdate>2021</risdate><abstract>The present invention relates to a SorCS2 crystal structure, the atomic coordinates obtained by X-ray crystallography of same, and their use in molecular modelling. The invention further relates to methods of growing crystals of SorCS2. Furthermore, the invention relates to peptides capable of binding to SorCS2, as well as their use as medicament, for example in the treatment of frontotemporal dementia.
La présente invention concerne une structure cristalline de SorCS2, ses coordonnées atomiques obtenues par cristallographie aux rayons X et leur utilisation dans la modélisation moléculaire. L'invention concerne en outre des procédés de croissance de cristaux de SorCS2. L'invention concerne par ailleurs des peptides capables de se lier à SorCS2, ainsi que leur utilisation comme médicament, par exemple dans le traitement de la démence frontotemporale.</abstract><oa>free_for_read</oa></addata></record> |
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| title | SORCS2 CRYSTAL STRUCTURE AND USES THEREOF |
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