MULTIPLEX SHRNA FOR USE IN VECTORS
New polynucleotides and new expression vectors for multiplexed microRNA-based shRNAs are provided. The shRNAs generated from these polynucleotides and vectors can knock down the expression of multiple genes without undesirable levels of off-target effects. L'invention concerne de nouveaux polyn...
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| creator | MACHADO, Hidevaldo Bueno CHOU, Eldon Thomas |
| description | New polynucleotides and new expression vectors for multiplexed microRNA-based shRNAs are provided. The shRNAs generated from these polynucleotides and vectors can knock down the expression of multiple genes without undesirable levels of off-target effects.
L'invention concerne de nouveaux polynucléotides et de nouveaux vecteurs d'expression pour des ARNsh à base de micro-ARN multiplexés. Les ARNsh générés à partir de ces polynucléotides et vecteurs peuvent inactiver l'expression de multiples gènes sans niveaux indésirables d'effets hors cible. |
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L'invention concerne de nouveaux polynucléotides et de nouveaux vecteurs d'expression pour des ARNsh à base de micro-ARN multiplexés. Les ARNsh générés à partir de ces polynucléotides et vecteurs peuvent inactiver l'expression de multiples gènes sans niveaux indésirables d'effets hors cible.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210107&DB=EPODOC&CC=WO&NR=2020223118A8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210107&DB=EPODOC&CC=WO&NR=2020223118A8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MACHADO, Hidevaldo Bueno</creatorcontrib><creatorcontrib>CHOU, Eldon Thomas</creatorcontrib><title>MULTIPLEX SHRNA FOR USE IN VECTORS</title><description>New polynucleotides and new expression vectors for multiplexed microRNA-based shRNAs are provided. The shRNAs generated from these polynucleotides and vectors can knock down the expression of multiple genes without undesirable levels of off-target effects.
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | MULTIPLEX SHRNA FOR USE IN VECTORS |
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