PROCESS FOR THE PREPARATION OF A KEY INTERMEDIATE OF GEMFIBROZIL

The present invention relates to an improved process for the preparation of 5-bromo-2,2-dimethyl-pentanoic acid isobutyl ester of formula (I), a key intermediate of Gemfibrozil, by using radical initiator in an environment friendly and commercially viable manner with safer conditions in high yield a...

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Hauptverfasser: DUDDEDA, Srinivas, NAVALE, Pravin Mahadu, SURYAWANSHI, Sandeep, PATIL, Vikrant Maruti, NAMBIAR, Sudhir, SALALKAR, Somnath Nandkumar, KUBAVAT, Hitesh Trambak
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creator DUDDEDA, Srinivas
NAVALE, Pravin Mahadu
SURYAWANSHI, Sandeep
PATIL, Vikrant Maruti
NAMBIAR, Sudhir
SALALKAR, Somnath Nandkumar
KUBAVAT, Hitesh Trambak
description The present invention relates to an improved process for the preparation of 5-bromo-2,2-dimethyl-pentanoic acid isobutyl ester of formula (I), a key intermediate of Gemfibrozil, by using radical initiator in an environment friendly and commercially viable manner with safer conditions in high yield and high chemical purity. La présente invention concerne un procédé amélioré pour la préparation d'ester d'isobutyle d'acide 5-bromo -2,2-diméthyl-pentanoïque de formule (I), un intermédiaire clé de gemfibrosil, à l'aide d'un initiateur de radicaux dans un environnement respectueux de l'environnement et viable du point de vue commercial avec des conditions plus sûres, avec un rendement élevé et une pureté chimique élevée.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PROCESS FOR THE PREPARATION OF A KEY INTERMEDIATE OF GEMFIBROZIL
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