MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES
Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1 -restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also pro...
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| creator | WANG, Chyung-Ru KATS, Dina SHANG, Shaobin SCOTT, Evan |
| description | Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1 -restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided.
La présente invention concerne des compositions de vaccin sous-unitaire comprenant un nanovecteur et un antigène lipidique, un antigène peptidique ou des combinaisons de ceux-ci qui induisent à la fois une réponse de lymphocyte T restreint par CD1 et une réponse de lymphocyte T restreint par le CMH chez un sujet. L'invention concerne aussi des procédés de fabrication et d'utilisation des compositions vaccinales sous-unitaires. |
| format | Patent |
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La présente invention concerne des compositions de vaccin sous-unitaire comprenant un nanovecteur et un antigène lipidique, un antigène peptidique ou des combinaisons de ceux-ci qui induisent à la fois une réponse de lymphocyte T restreint par CD1 et une réponse de lymphocyte T restreint par le CMH chez un sujet. L'invention concerne aussi des procédés de fabrication et d'utilisation des compositions vaccinales sous-unitaires.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201008&DB=EPODOC&CC=WO&NR=2020206307A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201008&DB=EPODOC&CC=WO&NR=2020206307A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG, Chyung-Ru</creatorcontrib><creatorcontrib>KATS, Dina</creatorcontrib><creatorcontrib>SHANG, Shaobin</creatorcontrib><creatorcontrib>SCOTT, Evan</creatorcontrib><title>MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES</title><description>Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1 -restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided.
La présente invention concerne des compositions de vaccin sous-unitaire comprenant un nanovecteur et un antigène lipidique, un antigène peptidique ou des combinaisons de ceux-ci qui induisent à la fois une réponse de lymphocyte T restreint par CD1 et une réponse de lymphocyte T restreint par le CMH chez un sujet. L'invention concerne aussi des procédés de fabrication et d'utilisation des compositions vaccinales sous-unitaires.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNikEKwjAQAHPxIOofFjwHWgt6TjcrCaSJNJt6LKWkJ9FC_T9W8AEyh4FhtsI3ybGVMdXJW4ZOIVpPETgAOYtrqgMbaAxKUF4D6lK2FLm1yKSBAck5WMst-EhxLzbT8Fjy4eedOF6J0cg8v_q8zMOYn_nd38Op-HKuiosqq_-uD6DmLvU</recordid><startdate>20201008</startdate><enddate>20201008</enddate><creator>WANG, Chyung-Ru</creator><creator>KATS, Dina</creator><creator>SHANG, Shaobin</creator><creator>SCOTT, Evan</creator><scope>EVB</scope></search><sort><creationdate>20201008</creationdate><title>MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES</title><author>WANG, Chyung-Ru ; KATS, Dina ; SHANG, Shaobin ; SCOTT, Evan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020206307A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG, Chyung-Ru</creatorcontrib><creatorcontrib>KATS, Dina</creatorcontrib><creatorcontrib>SHANG, Shaobin</creatorcontrib><creatorcontrib>SCOTT, Evan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG, Chyung-Ru</au><au>KATS, Dina</au><au>SHANG, Shaobin</au><au>SCOTT, Evan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES</title><date>2020-10-08</date><risdate>2020</risdate><abstract>Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1 -restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided.
La présente invention concerne des compositions de vaccin sous-unitaire comprenant un nanovecteur et un antigène lipidique, un antigène peptidique ou des combinaisons de ceux-ci qui induisent à la fois une réponse de lymphocyte T restreint par CD1 et une réponse de lymphocyte T restreint par le CMH chez un sujet. L'invention concerne aussi des procédés de fabrication et d'utilisation des compositions vaccinales sous-unitaires.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES |
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