PHARMACEUTICAL COMBINATION COMPRISING TNO155 AND A KRASG12C INHIBITOR

The present invention relates to a pharmaceutical combination comprising TNO155 and a KRASG12C inhibitor; pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of conditions in a SHP2 inhibitor combined with KRASG12C i...

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Bibliographische Detailangaben
Hauptverfasser:	BRACHMANN, Saskia Maria, MADDALO, Danilo, PRAHALLAD, Anirudh Cadapa
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical combination comprising TNO155 and a KRASG12C inhibitor; pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of conditions in a SHP2 inhibitor combined with KRASG12C inhibition is beneficial in, for example, the treatment of cancers. La présente invention concerne une combinaison pharmaceutique comprenant du TNO155 et un inhibiteur de KRASG12C ; des compositions pharmaceutiques comprenant celle-ci ; et des méthodes d'utilisation de telles combinaisons et compositions dans le traitement ou la prévention de maladies pour lesquelles un inhibiteur de SHP2 associé à l'inhibition de KRASG12C est bénéfique, par exemple, dans le traitement de cancers.