FUNCTIONALISED AMINE DERIVATIVES AS IL-17 MODULATORS

A series of functionalised amine derivatives of formula (I) as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders. Selon l'invention, une série...

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Hauptverfasser: SELBY, Matthew Duncan, FOLEY, Anne Marie, MONCK, Nathaniel Julius Thomas, YANG, Lihu, XUAN, Mengyang, HEER, Jag Paul, LECOMTE, Fabien Claude
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creator SELBY, Matthew Duncan
FOLEY, Anne Marie
MONCK, Nathaniel Julius Thomas
YANG, Lihu
XUAN, Mengyang
HEER, Jag Paul
LECOMTE, Fabien Claude
description A series of functionalised amine derivatives of formula (I) as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders. Selon l'invention, une série de dérivés amine fonctionnalisés de formule (I) tels que définis dans ce document, qui sont des modulateurs puissants de l'activité de l'IL-17 humaine, et sont donc utiles dans le traitement et/ou la prévention de diverses maladies humaines, notamment des troubles inflammatoires et auto-immuns.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FUNCTIONALISED AMINE DERIVATIVES AS IL-17 MODULATORS
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