DEEP EUTECTIC SOLVENT PLATFORM FOR ORAL PHARMACEUTICAL FORMULATIONS
The present invention relates to Eutectic Mixtures (EM), and preferably Deep Eutectic Solvents (DES), that are used in or as oral pharmaceutical formulation platforms. These platforms improve the solubility and bioavailability of active pharmaceutical ingredients (API), and especially of poorly wate...
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| creator | HODGINS, Niall KLUFT, Bastiaan |
| description | The present invention relates to Eutectic Mixtures (EM), and preferably Deep Eutectic Solvents (DES), that are used in or as oral pharmaceutical formulation platforms. These platforms improve the solubility and bioavailability of active pharmaceutical ingredients (API), and especially of poorly water-soluble APIs. The deep eutectic solvent (DES) compositions of the invention make use of a combination of a glycol with a polymer solubilizer component in specific molar ratios.
Mélanges eutectiques (EM), et de préférence solvants eutectiques profonds (DES), qui sont utilisés dans ou en tant que plateformes de formulation pharmaceutique orale. Ces plateformes améliorent la solubilité et la biodisponibilité d'ingrédients pharmaceutiques actifs (API), et notamment d'API faiblement solubles dans l'eau. Les compositions de solvant eutectique profond (DES) de l'invention utilisent une combinaison d'un glycol avec un composant solubilisant polymère selon des rapports molaires spécifiques. |
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Mélanges eutectiques (EM), et de préférence solvants eutectiques profonds (DES), qui sont utilisés dans ou en tant que plateformes de formulation pharmaceutique orale. Ces plateformes améliorent la solubilité et la biodisponibilité d'ingrédients pharmaceutiques actifs (API), et notamment d'API faiblement solubles dans l'eau. Les compositions de solvant eutectique profond (DES) de l'invention utilisent une combinaison d'un glycol avec un composant solubilisant polymère selon des rapports molaires spécifiques.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200430&DB=EPODOC&CC=WO&NR=2020085904A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200430&DB=EPODOC&CC=WO&NR=2020085904A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HODGINS, Niall</creatorcontrib><creatorcontrib>KLUFT, Bastiaan</creatorcontrib><title>DEEP EUTECTIC SOLVENT PLATFORM FOR ORAL PHARMACEUTICAL FORMULATIONS</title><description>The present invention relates to Eutectic Mixtures (EM), and preferably Deep Eutectic Solvents (DES), that are used in or as oral pharmaceutical formulation platforms. These platforms improve the solubility and bioavailability of active pharmaceutical ingredients (API), and especially of poorly water-soluble APIs. The deep eutectic solvent (DES) compositions of the invention make use of a combination of a glycol with a polymer solubilizer component in specific molar ratios.
Mélanges eutectiques (EM), et de préférence solvants eutectiques profonds (DES), qui sont utilisés dans ou en tant que plateformes de formulation pharmaceutique orale. Ces plateformes améliorent la solubilité et la biodisponibilité d'ingrédients pharmaceutiques actifs (API), et notamment d'API faiblement solubles dans l'eau. Les compositions de solvant eutectique profond (DES) de l'invention utilisent une combinaison d'un glycol avec un composant solubilisant polymère selon des rapports molaires spécifiques.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB2cXUNUHANDXF1DvF0Vgj29wlz9QtRCPBxDHHzD_JVABIK_kGOPgoBHo5Bvo7OQJWezkAuSDIUqMjT3y-Yh4E1LTGnOJUXSnMzKLu5hjh76KYW5MenFhckJqfmpZbEh_sbGRgZGFiYWhqYOBoZE6cKAPpNLLc</recordid><startdate>20200430</startdate><enddate>20200430</enddate><creator>HODGINS, Niall</creator><creator>KLUFT, Bastiaan</creator><scope>EVB</scope></search><sort><creationdate>20200430</creationdate><title>DEEP EUTECTIC SOLVENT PLATFORM FOR ORAL PHARMACEUTICAL FORMULATIONS</title><author>HODGINS, Niall ; KLUFT, Bastiaan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020085904A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>HODGINS, Niall</creatorcontrib><creatorcontrib>KLUFT, Bastiaan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HODGINS, Niall</au><au>KLUFT, Bastiaan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DEEP EUTECTIC SOLVENT PLATFORM FOR ORAL PHARMACEUTICAL FORMULATIONS</title><date>2020-04-30</date><risdate>2020</risdate><abstract>The present invention relates to Eutectic Mixtures (EM), and preferably Deep Eutectic Solvents (DES), that are used in or as oral pharmaceutical formulation platforms. These platforms improve the solubility and bioavailability of active pharmaceutical ingredients (API), and especially of poorly water-soluble APIs. The deep eutectic solvent (DES) compositions of the invention make use of a combination of a glycol with a polymer solubilizer component in specific molar ratios.
Mélanges eutectiques (EM), et de préférence solvants eutectiques profonds (DES), qui sont utilisés dans ou en tant que plateformes de formulation pharmaceutique orale. Ces plateformes améliorent la solubilité et la biodisponibilité d'ingrédients pharmaceutiques actifs (API), et notamment d'API faiblement solubles dans l'eau. Les compositions de solvant eutectique profond (DES) de l'invention utilisent une combinaison d'un glycol avec un composant solubilisant polymère selon des rapports molaires spécifiques.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | DEEP EUTECTIC SOLVENT PLATFORM FOR ORAL PHARMACEUTICAL FORMULATIONS |
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