INOSITOL PHOSPHATES FOR THE TREATMENT OF ECTOPIC CALCIFICATION
The present disclosure related to compositions, methods, dosages, dosage regimens, articles of manufacture and kits for the treatment and/or prevention ectopic calcifications, and in particular cutaneous calcifications such as calciphylaxis calcifications comprising inositol phosphate, inositol phos...
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| creator | PERELLÓ BESTARD, Joan SALCEDO ROCA, Carolina CANALS HAMANN, Ana-Zeralda |
| description | The present disclosure related to compositions, methods, dosages, dosage regimens, articles of manufacture and kits for the treatment and/or prevention ectopic calcifications, and in particular cutaneous calcifications such as calciphylaxis calcifications comprising inositol phosphate, inositol phosphate analogs, inositol phosphate derivatives, or combinations thereof. In a particular aspect the disclosure provides a dosage regimen to treat calciphylaxis comprising the administration of 6 mg/kg to 9 mg/kg daily doses of myo-inositol hexaphosphate, three times a week, for at least 1 to 8 months.
La présente invention concerne des compositions, des procédés, des dosages, des régimes posologiques, des articles manufacturés et des kits pour le traitement et/ ou la prévention des calcifications ectopiques et en particulier des calcifications cutanées, telles que des calcifications de calciphylaxie comprenant du phosphate d'inositol, des analogues de phosphate d'inositol, des dérivés de phosphate d'inositol, ou des combinaisons de ceux-ci. Dans un aspect particulier, l'invention concerne un régime posologique pour traiter la calciphylaxie, comprenant l'administration de 6 mg/ kg à 9 mg/ kg de doses quotidiennes de myo-inositol hexaphosphate, trois fois par semaine, pendant au moins 1 à 8 mois. |
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La présente invention concerne des compositions, des procédés, des dosages, des régimes posologiques, des articles manufacturés et des kits pour le traitement et/ ou la prévention des calcifications ectopiques et en particulier des calcifications cutanées, telles que des calcifications de calciphylaxie comprenant du phosphate d'inositol, des analogues de phosphate d'inositol, des dérivés de phosphate d'inositol, ou des combinaisons de ceux-ci. Dans un aspect particulier, l'invention concerne un régime posologique pour traiter la calciphylaxie, comprenant l'administration de 6 mg/ kg à 9 mg/ kg de doses quotidiennes de myo-inositol hexaphosphate, trois fois par semaine, pendant au moins 1 à 8 mois.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200416&DB=EPODOC&CC=WO&NR=2020074944A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200416&DB=EPODOC&CC=WO&NR=2020074944A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PERELLÓ BESTARD, Joan</creatorcontrib><creatorcontrib>SALCEDO ROCA, Carolina</creatorcontrib><creatorcontrib>CANALS HAMANN, Ana-Zeralda</creatorcontrib><title>INOSITOL PHOSPHATES FOR THE TREATMENT OF ECTOPIC CALCIFICATION</title><description>The present disclosure related to compositions, methods, dosages, dosage regimens, articles of manufacture and kits for the treatment and/or prevention ectopic calcifications, and in particular cutaneous calcifications such as calciphylaxis calcifications comprising inositol phosphate, inositol phosphate analogs, inositol phosphate derivatives, or combinations thereof. In a particular aspect the disclosure provides a dosage regimen to treat calciphylaxis comprising the administration of 6 mg/kg to 9 mg/kg daily doses of myo-inositol hexaphosphate, three times a week, for at least 1 to 8 months.
La présente invention concerne des compositions, des procédés, des dosages, des régimes posologiques, des articles manufacturés et des kits pour le traitement et/ ou la prévention des calcifications ectopiques et en particulier des calcifications cutanées, telles que des calcifications de calciphylaxie comprenant du phosphate d'inositol, des analogues de phosphate d'inositol, des dérivés de phosphate d'inositol, ou des combinaisons de ceux-ci. Dans un aspect particulier, l'invention concerne un régime posologique pour traiter la calciphylaxie, comprenant l'administration de 6 mg/ kg à 9 mg/ kg de doses quotidiennes de myo-inositol hexaphosphate, trois fois par semaine, pendant au moins 1 à 8 mois.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDz9PMP9gzx91EI8PAPDvBwDHENVnDzD1II8XBVCAlydQzxdfULUfB3U3B1DvEP8HRWcHb0cfZ083R2DPH09-NhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGRgYG5iaWJiaOhsbEqQIAFIkrJg</recordid><startdate>20200416</startdate><enddate>20200416</enddate><creator>PERELLÓ BESTARD, Joan</creator><creator>SALCEDO ROCA, Carolina</creator><creator>CANALS HAMANN, Ana-Zeralda</creator><scope>EVB</scope></search><sort><creationdate>20200416</creationdate><title>INOSITOL PHOSPHATES FOR THE TREATMENT OF ECTOPIC CALCIFICATION</title><author>PERELLÓ BESTARD, Joan ; SALCEDO ROCA, Carolina ; CANALS HAMANN, Ana-Zeralda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020074944A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PERELLÓ BESTARD, Joan</creatorcontrib><creatorcontrib>SALCEDO ROCA, Carolina</creatorcontrib><creatorcontrib>CANALS HAMANN, Ana-Zeralda</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PERELLÓ BESTARD, Joan</au><au>SALCEDO ROCA, Carolina</au><au>CANALS HAMANN, Ana-Zeralda</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INOSITOL PHOSPHATES FOR THE TREATMENT OF ECTOPIC CALCIFICATION</title><date>2020-04-16</date><risdate>2020</risdate><abstract>The present disclosure related to compositions, methods, dosages, dosage regimens, articles of manufacture and kits for the treatment and/or prevention ectopic calcifications, and in particular cutaneous calcifications such as calciphylaxis calcifications comprising inositol phosphate, inositol phosphate analogs, inositol phosphate derivatives, or combinations thereof. In a particular aspect the disclosure provides a dosage regimen to treat calciphylaxis comprising the administration of 6 mg/kg to 9 mg/kg daily doses of myo-inositol hexaphosphate, three times a week, for at least 1 to 8 months.
La présente invention concerne des compositions, des procédés, des dosages, des régimes posologiques, des articles manufacturés et des kits pour le traitement et/ ou la prévention des calcifications ectopiques et en particulier des calcifications cutanées, telles que des calcifications de calciphylaxie comprenant du phosphate d'inositol, des analogues de phosphate d'inositol, des dérivés de phosphate d'inositol, ou des combinaisons de ceux-ci. Dans un aspect particulier, l'invention concerne un régime posologique pour traiter la calciphylaxie, comprenant l'administration de 6 mg/ kg à 9 mg/ kg de doses quotidiennes de myo-inositol hexaphosphate, trois fois par semaine, pendant au moins 1 à 8 mois.</abstract><oa>free_for_read</oa></addata></record> |
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| title | INOSITOL PHOSPHATES FOR THE TREATMENT OF ECTOPIC CALCIFICATION |
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