METHODS OF PRODUCING PYRAZOLE COMPOUNDS

The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also dire...

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Hauptverfasser: KASUNDRA, Ashok, CHHIPA, Laxmikant, SINGARAVEL, Mohan, GUPTA, Ramesh
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creator KASUNDRA, Ashok
CHHIPA, Laxmikant
SINGARAVEL, Mohan
GUPTA, Ramesh
description The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof. La présente invention concerne des procédés de production de composés à base de pyrazole substitué par l'intermédiaire de nouveaux intermédiaires et des procédés uniques de préparation de tels intermédiaires qui permettent la synthèse de produit final par l'intermédiaire d'une voie de synthèse viable dans le commerce. La présente invention concerne également de nouveaux procédés de production de composés de type thyroïde à base de pyrazole substitué, et des formes solides de 3-{4-[(7-hydroxy-6-méthyl-indan-4-yl) méthyl]-3,5-diméthyl-1 H-pyrazol-1-yl}-propanoïque, ses compositions pharmaceutiques et leurs procédés de préparation.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title METHODS OF PRODUCING PYRAZOLE COMPOUNDS
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