ACELLULAR ORGANS, AND METHODS OF PRODUCING THE SAME

Provided are methods of producing an acellular organ. The method includes the steps of, subjecting an organ derived from an animal to a static supercritical fluid (SCF) treatment followed by a dynamic SCF treatment. Optionally, the method of the present disclosure further includes a hypertonic and a...

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Hauptverfasser: PERIASAMY, Srinivasan, KUO, Jer-Cheng, WEI, Chao-Yi, HSIEH, Dar-Jen, LAI, Yi-Ping, CHAO, Chao-Chin
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creator PERIASAMY, Srinivasan
KUO, Jer-Cheng
WEI, Chao-Yi
HSIEH, Dar-Jen
LAI, Yi-Ping
CHAO, Chao-Chin
description Provided are methods of producing an acellular organ. The method includes the steps of, subjecting an organ derived from an animal to a static supercritical fluid (SCF) treatment followed by a dynamic SCF treatment. Optionally, the method of the present disclosure further includes a hypertonic and a hypotonic treatments prior to the static SCF treatment, and/or a neutralizing treatment after the dynamic SCF treatment. Also disclosed herein are acellular organs produced by the present method. La présente invention concerne des procédés de production d'un organe acellulaire. Le procédé comprend les étapes consistant à soumettre un organe issu d'un animal à un traitement statique par un fluide supercritique (FSC), suivi d'un traitement dynamique par un FSC. Éventuellement, le procédé de la présente invention comprend en outre un traitement hypertonique et un traitement hypotonique avant le traitement statique par un FSC et/ou un traitement de neutralisation après le traitement dynamique par un FSC. L'invention concerne également des organes acellulaires produits par le présent procédé.
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subjects BANDAGES, DRESSINGS OR ABSORBENT PADS
BEER
BIOCHEMISTRY
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
ENZYMOLOGY
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
PROSTHESES
SPIRITS
TREATMENT OR PROTECTION OF EYES OR EARS
VINEGAR
WINE
title ACELLULAR ORGANS, AND METHODS OF PRODUCING THE SAME
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