PLATINUM SULFIDE PROTEIN NANOPARTICLE HAVING NEAR-INFRARED PHOTOTHERMAL EFFECT AND MULTI-MODAL IMAGING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
A platinum sulfide protein nanoparticle having near-infrared photothermal effect and multi-modal imaging function, a preparation method therefor and an application thereof. The platinum sulfide nanoparticle having near-infrared photothermal effect and multi-modal imaging function is prepared in aque...
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creator | YANG, Hong XU, Tao WANG, Xue ZHANG, Miya KE, Hengte CHEN, Huabing LI, Ming |
description | A platinum sulfide protein nanoparticle having near-infrared photothermal effect and multi-modal imaging function, a preparation method therefor and an application thereof. The platinum sulfide nanoparticle having near-infrared photothermal effect and multi-modal imaging function is prepared in aqueous phase by means of formulation screening and process limitation. The nanoparticle has an ultra-small particle size and good stability as well as tumor targeting and photothermal effects and integrates functions of near-infrared imaging, CT imaging, and thermal imaging, so as to achieve high sensitivity, high resolution, and precise positioning of tumors, and to produce high-efficiency photothermal effects under the excitation of near-infrared light to kill tumor cells by thermal ablation, thereby achieving the purpose of efficient, safe, visual, and accurate treatment of tumors. The nanoparticle has the potential for further development and clinical application.
L'invention concerne une nanoparticule de protéine |
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L'invention concerne une nanoparticule de protéine</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjD1OAzEQhbehQMAdRkrLSsvSkHJkj-OR7BnLzEIZRZGpUBIpOVIOym7gAFRP7--7764lobFMGd6nFNgTlKpGLCAoWrAau0QQ8YNlA0JYe5ZQsZKHEtXUItWMCSgEcgYoHvKUjPusfo4542Z5hkmcscrzzKcZi4uBTBbVw8KgoPX2xlISu9_-Vmh47O6-dt_n9vSnD90qkLnYt9Nx286n3b4d2mX7qeMwDsO4HtZv-PL6v9UP9l9HUA</recordid><startdate>20200213</startdate><enddate>20200213</enddate><creator>YANG, Hong</creator><creator>XU, Tao</creator><creator>WANG, Xue</creator><creator>ZHANG, Miya</creator><creator>KE, Hengte</creator><creator>CHEN, Huabing</creator><creator>LI, Ming</creator><scope>EVB</scope></search><sort><creationdate>20200213</creationdate><title>PLATINUM SULFIDE PROTEIN NANOPARTICLE HAVING NEAR-INFRARED PHOTOTHERMAL EFFECT AND MULTI-MODAL IMAGING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF</title><author>YANG, Hong ; XU, Tao ; WANG, Xue ; ZHANG, Miya ; KE, Hengte ; CHEN, Huabing ; LI, Ming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020029098A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng ; fre</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>YANG, Hong</creatorcontrib><creatorcontrib>XU, Tao</creatorcontrib><creatorcontrib>WANG, Xue</creatorcontrib><creatorcontrib>ZHANG, Miya</creatorcontrib><creatorcontrib>KE, Hengte</creatorcontrib><creatorcontrib>CHEN, Huabing</creatorcontrib><creatorcontrib>LI, Ming</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YANG, Hong</au><au>XU, Tao</au><au>WANG, Xue</au><au>ZHANG, Miya</au><au>KE, Hengte</au><au>CHEN, Huabing</au><au>LI, Ming</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PLATINUM SULFIDE PROTEIN NANOPARTICLE HAVING NEAR-INFRARED PHOTOTHERMAL EFFECT AND MULTI-MODAL IMAGING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF</title><date>2020-02-13</date><risdate>2020</risdate><abstract>A platinum sulfide protein nanoparticle having near-infrared photothermal effect and multi-modal imaging function, a preparation method therefor and an application thereof. The platinum sulfide nanoparticle having near-infrared photothermal effect and multi-modal imaging function is prepared in aqueous phase by means of formulation screening and process limitation. The nanoparticle has an ultra-small particle size and good stability as well as tumor targeting and photothermal effects and integrates functions of near-infrared imaging, CT imaging, and thermal imaging, so as to achieve high sensitivity, high resolution, and precise positioning of tumors, and to produce high-efficiency photothermal effects under the excitation of near-infrared light to kill tumor cells by thermal ablation, thereby achieving the purpose of efficient, safe, visual, and accurate treatment of tumors. The nanoparticle has the potential for further development and clinical application.
L'invention concerne une nanoparticule de protéine</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PLATINUM SULFIDE PROTEIN NANOPARTICLE HAVING NEAR-INFRARED PHOTOTHERMAL EFFECT AND MULTI-MODAL IMAGING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF |
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