PROCESS FOR PREPARING BUFFER SOLUTIONS FOR IN VITRO TESTING OF THE SOLUBILITY OF MEDICAMENTS, PACKAGING FOR PRODUCING THE BUFFER SOLUTION AND KIT FOR TESTING CLINICAL STATES
A method for preparing a buffer solution suitable for physiologically relevant in vitro drug dissolution testing, drug solubility testing and/or drug profiling, the method comprising: (a) dispensing from a deformable container into a second container a predetermined quantity of a concentrate of the...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LEIGH, Mathew Louis Steven DOS SANTOS, Vasco Rafael Fernandes LEIGH, Daryl Louis Van MCCULLOUGH, Orfhlaith Tess LEIGH, Steven |
| description | A method for preparing a buffer solution suitable for physiologically relevant in vitro drug dissolution testing, drug solubility testing and/or drug profiling, the method comprising: (a) dispensing from a deformable container into a second container a predetermined quantity of a concentrate of the buffer solution, said deformable container having an orifice or aperture configured to dispense the concentrate in a dropwise manner and/or in a controlled stream, and (b) diluting the predetermined quantity of the concentrate with a predetermined quantity of a solvent to produce the buffer solution. A pack comprising a container and a concentrate of said buffer solution within the container, and a method for preparing the said pack, are also provided.
L'invention concerne un procédé permettant de préparer une solution tampon appropriée pour un test de dissolution de médicament in vitro physiologiquement pertinent, un test de solubilité de médicament et/ou un profilage de médicament, ledit procédé consistant à : (a) distribuer, d'un récipient déformable à un second récipient, une quantité prédéterminée d'un concentré de la solution tampon, ledit récipient déformable comprenant un orifice ou une ouverture configuré pour distribuer le concentré sous forme de gouttes et/ou dans un flux contrôlé ; et (b) diluer la quantité prédéterminée du concentré avec une quantité prédéterminée d'un solvant pour produire la solution tampon. L'invention concerne également un emballage comprenant un récipient et un concentré de ladite solution tampon dans le récipient, ainsi qu'un procédé permettant de préparer ledit emballage. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2019239133A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2019239133A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2019239133A13</originalsourceid><addsrcrecordid>eNqNjTELwjAQhbs4iPofDlwVrJkcY5q0R9skJFfFSYrESbRQ_5b_UWN1cXJ63LvvvTdOHtYZIb0HZRxYJy13qHPYNkpJB95UDaHRwxs17JCcAZKeImUUUCHf1BYrpEN0apmh4LXU5BdguSh5Htmh32SNiFeM_WwA1xmUSG_yuyAq1K-2CjzxlzdNRuf20ofZRyfJXEkSxTJ0t2Pou_YUruF-3Jv1Kt2s2SZljKfsP-oJU8pJgQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR PREPARING BUFFER SOLUTIONS FOR IN VITRO TESTING OF THE SOLUBILITY OF MEDICAMENTS, PACKAGING FOR PRODUCING THE BUFFER SOLUTION AND KIT FOR TESTING CLINICAL STATES</title><source>esp@cenet</source><creator>LEIGH, Mathew Louis Steven ; DOS SANTOS, Vasco Rafael Fernandes ; LEIGH, Daryl Louis Van ; MCCULLOUGH, Orfhlaith Tess ; LEIGH, Steven</creator><creatorcontrib>LEIGH, Mathew Louis Steven ; DOS SANTOS, Vasco Rafael Fernandes ; LEIGH, Daryl Louis Van ; MCCULLOUGH, Orfhlaith Tess ; LEIGH, Steven</creatorcontrib><description>A method for preparing a buffer solution suitable for physiologically relevant in vitro drug dissolution testing, drug solubility testing and/or drug profiling, the method comprising: (a) dispensing from a deformable container into a second container a predetermined quantity of a concentrate of the buffer solution, said deformable container having an orifice or aperture configured to dispense the concentrate in a dropwise manner and/or in a controlled stream, and (b) diluting the predetermined quantity of the concentrate with a predetermined quantity of a solvent to produce the buffer solution. A pack comprising a container and a concentrate of said buffer solution within the container, and a method for preparing the said pack, are also provided.
L'invention concerne un procédé permettant de préparer une solution tampon appropriée pour un test de dissolution de médicament in vitro physiologiquement pertinent, un test de solubilité de médicament et/ou un profilage de médicament, ledit procédé consistant à : (a) distribuer, d'un récipient déformable à un second récipient, une quantité prédéterminée d'un concentré de la solution tampon, ledit récipient déformable comprenant un orifice ou une ouverture configuré pour distribuer le concentré sous forme de gouttes et/ou dans un flux contrôlé ; et (b) diluer la quantité prédéterminée du concentré avec une quantité prédéterminée d'un solvant pour produire la solution tampon. L'invention concerne également un emballage comprenant un récipient et un concentré de ladite solution tampon dans le récipient, ainsi qu'un procédé permettant de préparer ledit emballage.</description><language>eng ; fre</language><subject>ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR ; ADVERTISING ; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE ; CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS,e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES,DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS ; CONVEYING ; CRYPTOGRAPHY ; DIAGRAMS ; DISPLAY ; EDUCATION ; EDUCATIONAL OR DEMONSTRATION APPLIANCES ; GLOBES ; HANDLING THIN OR FILAMENTARY MATERIAL ; MEASURING ; MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUIDLEVEL ; METERING BY VOLUME ; PACKAGES ; PACKAGING ELEMENTS ; PACKING ; PERFORMING OPERATIONS ; PHYSICS ; PLANETARIA ; SEALS ; STORING ; TESTING ; TRANSPORTING</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191219&DB=EPODOC&CC=WO&NR=2019239133A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191219&DB=EPODOC&CC=WO&NR=2019239133A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEIGH, Mathew Louis Steven</creatorcontrib><creatorcontrib>DOS SANTOS, Vasco Rafael Fernandes</creatorcontrib><creatorcontrib>LEIGH, Daryl Louis Van</creatorcontrib><creatorcontrib>MCCULLOUGH, Orfhlaith Tess</creatorcontrib><creatorcontrib>LEIGH, Steven</creatorcontrib><title>PROCESS FOR PREPARING BUFFER SOLUTIONS FOR IN VITRO TESTING OF THE SOLUBILITY OF MEDICAMENTS, PACKAGING FOR PRODUCING THE BUFFER SOLUTION AND KIT FOR TESTING CLINICAL STATES</title><description>A method for preparing a buffer solution suitable for physiologically relevant in vitro drug dissolution testing, drug solubility testing and/or drug profiling, the method comprising: (a) dispensing from a deformable container into a second container a predetermined quantity of a concentrate of the buffer solution, said deformable container having an orifice or aperture configured to dispense the concentrate in a dropwise manner and/or in a controlled stream, and (b) diluting the predetermined quantity of the concentrate with a predetermined quantity of a solvent to produce the buffer solution. A pack comprising a container and a concentrate of said buffer solution within the container, and a method for preparing the said pack, are also provided.
L'invention concerne un procédé permettant de préparer une solution tampon appropriée pour un test de dissolution de médicament in vitro physiologiquement pertinent, un test de solubilité de médicament et/ou un profilage de médicament, ledit procédé consistant à : (a) distribuer, d'un récipient déformable à un second récipient, une quantité prédéterminée d'un concentré de la solution tampon, ledit récipient déformable comprenant un orifice ou une ouverture configuré pour distribuer le concentré sous forme de gouttes et/ou dans un flux contrôlé ; et (b) diluer la quantité prédéterminée du concentré avec une quantité prédéterminée d'un solvant pour produire la solution tampon. L'invention concerne également un emballage comprenant un récipient et un concentré de ladite solution tampon dans le récipient, ainsi qu'un procédé permettant de préparer ledit emballage.</description><subject>ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR</subject><subject>ADVERTISING</subject><subject>APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE</subject><subject>CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS,e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES,DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS</subject><subject>CONVEYING</subject><subject>CRYPTOGRAPHY</subject><subject>DIAGRAMS</subject><subject>DISPLAY</subject><subject>EDUCATION</subject><subject>EDUCATIONAL OR DEMONSTRATION APPLIANCES</subject><subject>GLOBES</subject><subject>HANDLING THIN OR FILAMENTARY MATERIAL</subject><subject>MEASURING</subject><subject>MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUIDLEVEL</subject><subject>METERING BY VOLUME</subject><subject>PACKAGES</subject><subject>PACKAGING ELEMENTS</subject><subject>PACKING</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICS</subject><subject>PLANETARIA</subject><subject>SEALS</subject><subject>STORING</subject><subject>TESTING</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTELwjAQhbs4iPofDlwVrJkcY5q0R9skJFfFSYrESbRQ_5b_UWN1cXJ63LvvvTdOHtYZIb0HZRxYJy13qHPYNkpJB95UDaHRwxs17JCcAZKeImUUUCHf1BYrpEN0apmh4LXU5BdguSh5Htmh32SNiFeM_WwA1xmUSG_yuyAq1K-2CjzxlzdNRuf20ofZRyfJXEkSxTJ0t2Pou_YUruF-3Jv1Kt2s2SZljKfsP-oJU8pJgQ</recordid><startdate>20191219</startdate><enddate>20191219</enddate><creator>LEIGH, Mathew Louis Steven</creator><creator>DOS SANTOS, Vasco Rafael Fernandes</creator><creator>LEIGH, Daryl Louis Van</creator><creator>MCCULLOUGH, Orfhlaith Tess</creator><creator>LEIGH, Steven</creator><scope>EVB</scope></search><sort><creationdate>20191219</creationdate><title>PROCESS FOR PREPARING BUFFER SOLUTIONS FOR IN VITRO TESTING OF THE SOLUBILITY OF MEDICAMENTS, PACKAGING FOR PRODUCING THE BUFFER SOLUTION AND KIT FOR TESTING CLINICAL STATES</title><author>LEIGH, Mathew Louis Steven ; DOS SANTOS, Vasco Rafael Fernandes ; LEIGH, Daryl Louis Van ; MCCULLOUGH, Orfhlaith Tess ; LEIGH, Steven</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2019239133A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR</topic><topic>ADVERTISING</topic><topic>APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE</topic><topic>CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS,e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES,DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS</topic><topic>CONVEYING</topic><topic>CRYPTOGRAPHY</topic><topic>DIAGRAMS</topic><topic>DISPLAY</topic><topic>EDUCATION</topic><topic>EDUCATIONAL OR DEMONSTRATION APPLIANCES</topic><topic>GLOBES</topic><topic>HANDLING THIN OR FILAMENTARY MATERIAL</topic><topic>MEASURING</topic><topic>MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUIDLEVEL</topic><topic>METERING BY VOLUME</topic><topic>PACKAGES</topic><topic>PACKAGING ELEMENTS</topic><topic>PACKING</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICS</topic><topic>PLANETARIA</topic><topic>SEALS</topic><topic>STORING</topic><topic>TESTING</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>LEIGH, Mathew Louis Steven</creatorcontrib><creatorcontrib>DOS SANTOS, Vasco Rafael Fernandes</creatorcontrib><creatorcontrib>LEIGH, Daryl Louis Van</creatorcontrib><creatorcontrib>MCCULLOUGH, Orfhlaith Tess</creatorcontrib><creatorcontrib>LEIGH, Steven</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEIGH, Mathew Louis Steven</au><au>DOS SANTOS, Vasco Rafael Fernandes</au><au>LEIGH, Daryl Louis Van</au><au>MCCULLOUGH, Orfhlaith Tess</au><au>LEIGH, Steven</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING BUFFER SOLUTIONS FOR IN VITRO TESTING OF THE SOLUBILITY OF MEDICAMENTS, PACKAGING FOR PRODUCING THE BUFFER SOLUTION AND KIT FOR TESTING CLINICAL STATES</title><date>2019-12-19</date><risdate>2019</risdate><abstract>A method for preparing a buffer solution suitable for physiologically relevant in vitro drug dissolution testing, drug solubility testing and/or drug profiling, the method comprising: (a) dispensing from a deformable container into a second container a predetermined quantity of a concentrate of the buffer solution, said deformable container having an orifice or aperture configured to dispense the concentrate in a dropwise manner and/or in a controlled stream, and (b) diluting the predetermined quantity of the concentrate with a predetermined quantity of a solvent to produce the buffer solution. A pack comprising a container and a concentrate of said buffer solution within the container, and a method for preparing the said pack, are also provided.
L'invention concerne un procédé permettant de préparer une solution tampon appropriée pour un test de dissolution de médicament in vitro physiologiquement pertinent, un test de solubilité de médicament et/ou un profilage de médicament, ledit procédé consistant à : (a) distribuer, d'un récipient déformable à un second récipient, une quantité prédéterminée d'un concentré de la solution tampon, ledit récipient déformable comprenant un orifice ou une ouverture configuré pour distribuer le concentré sous forme de gouttes et/ou dans un flux contrôlé ; et (b) diluer la quantité prédéterminée du concentré avec une quantité prédéterminée d'un solvant pour produire la solution tampon. L'invention concerne également un emballage comprenant un récipient et un concentré de ladite solution tampon dans le récipient, ainsi qu'un procédé permettant de préparer ledit emballage.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2019239133A1 |
| source | esp@cenet |
| subjects | ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR ADVERTISING APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS,e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES,DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS CONVEYING CRYPTOGRAPHY DIAGRAMS DISPLAY EDUCATION EDUCATIONAL OR DEMONSTRATION APPLIANCES GLOBES HANDLING THIN OR FILAMENTARY MATERIAL MEASURING MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUIDLEVEL METERING BY VOLUME PACKAGES PACKAGING ELEMENTS PACKING PERFORMING OPERATIONS PHYSICS PLANETARIA SEALS STORING TESTING TRANSPORTING |
| title | PROCESS FOR PREPARING BUFFER SOLUTIONS FOR IN VITRO TESTING OF THE SOLUBILITY OF MEDICAMENTS, PACKAGING FOR PRODUCING THE BUFFER SOLUTION AND KIT FOR TESTING CLINICAL STATES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T01%3A19%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LEIGH,%20Mathew%20Louis%20Steven&rft.date=2019-12-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2019239133A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |