BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES
The present disclosure relates to the delivery of active agents, e.g., drug substances, using as carriers for their delivery biocompatible copolymers comprising side chain-linked amino acids having active agents bound to their alpha-amino and/or alpha-carboxyl groups, either directly or via linker m...
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creator | HACKEBEIL, Michael PANIGHETTI, Davide THOMMEN, Christophe GERATHS, Christian HITZ, Hans |
description | The present disclosure relates to the delivery of active agents, e.g., drug substances, using as carriers for their delivery biocompatible copolymers comprising side chain-linked amino acids having active agents bound to their alpha-amino and/or alpha-carboxyl groups, either directly or via linker molecules. The active agent-containing copolymers can be functionalized to contain cell type- or tissue type-specific targeting moieties.
La présente invention concerne l'administration d'agents actifs, par exemple des substances médicamenteuses, en utilisant comme supports pour leur administration des copolymères biocompatibles comprenant des acides aminés à chaîne latérale ayant des agents actifs liés à leurs groupes alpha-amino et/ou alpha-carboxyle, soit directement, soit par l'intermédiaire de molécules de liaison. Les copolymères contenant un agent actif peuvent être fonctionnalisés pour contenir des fractions de ciblage spécifiques de type cellulaire ou de type tissulaire. |
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La présente invention concerne l'administration d'agents actifs, par exemple des substances médicamenteuses, en utilisant comme supports pour leur administration des copolymères biocompatibles comprenant des acides aminés à chaîne latérale ayant des agents actifs liés à leurs groupes alpha-amino et/ou alpha-carboxyle, soit directement, soit par l'intermédiaire de molécules de liaison. Les copolymères contenant un agent actif peuvent être fonctionnalisés pour contenir des fractions de ciblage spécifiques de type cellulaire ou de type tissulaire.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191114&DB=EPODOC&CC=WO&NR=2019215207A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191114&DB=EPODOC&CC=WO&NR=2019215207A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HACKEBEIL, Michael</creatorcontrib><creatorcontrib>PANIGHETTI, Davide</creatorcontrib><creatorcontrib>THOMMEN, Christophe</creatorcontrib><creatorcontrib>GERATHS, Christian</creatorcontrib><creatorcontrib>HITZ, Hans</creatorcontrib><title>BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES</title><description>The present disclosure relates to the delivery of active agents, e.g., drug substances, using as carriers for their delivery biocompatible copolymers comprising side chain-linked amino acids having active agents bound to their alpha-amino and/or alpha-carboxyl groups, either directly or via linker molecules. The active agent-containing copolymers can be functionalized to contain cell type- or tissue type-specific targeting moieties.
La présente invention concerne l'administration d'agents actifs, par exemple des substances médicamenteuses, en utilisant comme supports pour leur administration des copolymères biocompatibles comprenant des acides aminés à chaîne latérale ayant des agents actifs liés à leurs groupes alpha-amino et/ou alpha-carboxyle, soit directement, soit par l'intermédiaire de molécules de liaison. Les copolymères contenant un agent actif peuvent être fonctionnalisés pour contenir des fractions de ciblage spécifiques de type cellulaire ou de type tissulaire.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBy8vR39vcNcAzxdPJxVXD2D_D3ifR1DQKy_EIcPf08_dwVfEN9QjwDgLKOziGeYUDK3dUvRMHX38fVOdTHNZiHgTUtMac4lRdKczMou7mGOHvophbkx6cWFyQmp-allsSH-xsZGFoaGZoaGZg7GhoTpwoA2nIscQ</recordid><startdate>20191114</startdate><enddate>20191114</enddate><creator>HACKEBEIL, Michael</creator><creator>PANIGHETTI, Davide</creator><creator>THOMMEN, Christophe</creator><creator>GERATHS, Christian</creator><creator>HITZ, Hans</creator><scope>EVB</scope></search><sort><creationdate>20191114</creationdate><title>BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES</title><author>HACKEBEIL, Michael ; PANIGHETTI, Davide ; THOMMEN, Christophe ; GERATHS, Christian ; HITZ, Hans</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2019215207A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HACKEBEIL, Michael</creatorcontrib><creatorcontrib>PANIGHETTI, Davide</creatorcontrib><creatorcontrib>THOMMEN, Christophe</creatorcontrib><creatorcontrib>GERATHS, Christian</creatorcontrib><creatorcontrib>HITZ, Hans</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HACKEBEIL, Michael</au><au>PANIGHETTI, Davide</au><au>THOMMEN, Christophe</au><au>GERATHS, Christian</au><au>HITZ, Hans</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES</title><date>2019-11-14</date><risdate>2019</risdate><abstract>The present disclosure relates to the delivery of active agents, e.g., drug substances, using as carriers for their delivery biocompatible copolymers comprising side chain-linked amino acids having active agents bound to their alpha-amino and/or alpha-carboxyl groups, either directly or via linker molecules. The active agent-containing copolymers can be functionalized to contain cell type- or tissue type-specific targeting moieties.
La présente invention concerne l'administration d'agents actifs, par exemple des substances médicamenteuses, en utilisant comme supports pour leur administration des copolymères biocompatibles comprenant des acides aminés à chaîne latérale ayant des agents actifs liés à leurs groupes alpha-amino et/ou alpha-carboxyle, soit directement, soit par l'intermédiaire de molécules de liaison. Les copolymères contenant un agent actif peuvent être fonctionnalisés pour contenir des fractions de ciblage spécifiques de type cellulaire ou de type tissulaire.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES |
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