BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES

The present disclosure relates to the delivery of active agents, e.g., drug substances, using as carriers for their delivery biocompatible copolymers comprising side chain-linked amino acids having active agents bound to their alpha-amino and/or alpha-carboxyl groups, either directly or via linker m...

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Hauptverfasser: HACKEBEIL, Michael, PANIGHETTI, Davide, THOMMEN, Christophe, GERATHS, Christian, HITZ, Hans
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creator HACKEBEIL, Michael
PANIGHETTI, Davide
THOMMEN, Christophe
GERATHS, Christian
HITZ, Hans
description The present disclosure relates to the delivery of active agents, e.g., drug substances, using as carriers for their delivery biocompatible copolymers comprising side chain-linked amino acids having active agents bound to their alpha-amino and/or alpha-carboxyl groups, either directly or via linker molecules. The active agent-containing copolymers can be functionalized to contain cell type- or tissue type-specific targeting moieties. La présente invention concerne l'administration d'agents actifs, par exemple des substances médicamenteuses, en utilisant comme supports pour leur administration des copolymères biocompatibles comprenant des acides aminés à chaîne latérale ayant des agents actifs liés à leurs groupes alpha-amino et/ou alpha-carboxyle, soit directement, soit par l'intermédiaire de molécules de liaison. Les copolymères contenant un agent actif peuvent être fonctionnalisés pour contenir des fractions de ciblage spécifiques de type cellulaire ou de type tissulaire.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES
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