ANTIBODIES AGAINST MICA AND/OR MICB AND USES THEREOF

The disclosure provides antibodies that specifically bind human MICA/B and methods of use thereof. In some aspects, the disclosure is directed to methods of treating a cancer in a subject, comprising administering to the subject an anti-MICA/B antibody. L'invention concerne des anticorps qui se...

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Bibliographische Detailangaben
Hauptverfasser:	SRINIVASAN, Mohan, HUANG, Haichun, KORMAN, Alan J, BEZMAN, Natalie A, HUANG, Richard Y, STROP, Pavel, CHEN, Guodong, LEE, Peter Sung Keun, CAMDERE, Gamze Ozlem, GRAZIANO, Robert F, KUHNE, Michelle Renee, YIN, Yiming
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The disclosure provides antibodies that specifically bind human MICA/B and methods of use thereof. In some aspects, the disclosure is directed to methods of treating a cancer in a subject, comprising administering to the subject an anti-MICA/B antibody. L'invention concerne des anticorps qui se lient spécifiquement à MICA/B humain et des procédés d'utilisation de ceux-ci. Dans certains aspects, l'invention concerne des procédés de traitement d'un cancer chez un sujet, comprenant l'administration au sujet d'un anticorps anti-MICA/B.