INJECTABLE OFF-THE- SHELF CARTILAGE, TENDON, AND LIGAMENT REPAIR COMPOSITIONS AND METHODS OF USE
Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellula...
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| creator | KELLY, Terri-Ann HUANG, Angela Hai BHUMRATANA, Sarindr BEANE, Olivia Spencer JEFFRIES, Eric Meade |
| description | Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellular matrices such collagen and glycosaminoglycan. Also provided are methods of treating connective tissue defects, cartilage injury, and cartilage degradation.
L'invention concerne des compositions comprenant un corps de cellule mésenchymateuse condensé et un hydrogel. Les compositions peuvent en outre comprendre des médicaments ou des facteurs de croissance. Le corps de cellule mésenchymateuse condensé peut comprendre une cellule de tissu conjonctif, voire une cellule progénitrice capable de produire des matrices extracellulaires de tissu conjonctif tel que le collagène et le glycosaminoglycane. Des méthodes de traitement de tissu conjonctif défectueux, de lésion cartilagineuse et de dégradation cartilagineuse sont en outre décrites. |
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L'invention concerne des compositions comprenant un corps de cellule mésenchymateuse condensé et un hydrogel. Les compositions peuvent en outre comprendre des médicaments ou des facteurs de croissance. Le corps de cellule mésenchymateuse condensé peut comprendre une cellule de tissu conjonctif, voire une cellule progénitrice capable de produire des matrices extracellulaires de tissu conjonctif tel que le collagène et le glycosaminoglycane. Des méthodes de traitement de tissu conjonctif défectueux, de lésion cartilagineuse et de dégradation cartilagineuse sont en outre décrites.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190912&DB=EPODOC&CC=WO&NR=2019173435A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190912&DB=EPODOC&CC=WO&NR=2019173435A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KELLY, Terri-Ann</creatorcontrib><creatorcontrib>HUANG, Angela Hai</creatorcontrib><creatorcontrib>BHUMRATANA, Sarindr</creatorcontrib><creatorcontrib>BEANE, Olivia Spencer</creatorcontrib><creatorcontrib>JEFFRIES, Eric Meade</creatorcontrib><title>INJECTABLE OFF-THE- SHELF CARTILAGE, TENDON, AND LIGAMENT REPAIR COMPOSITIONS AND METHODS OF USE</title><description>Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellular matrices such collagen and glycosaminoglycan. Also provided are methods of treating connective tissue defects, cartilage injury, and cartilage degradation.
L'invention concerne des compositions comprenant un corps de cellule mésenchymateuse condensé et un hydrogel. Les compositions peuvent en outre comprendre des médicaments ou des facteurs de croissance. Le corps de cellule mésenchymateuse condensé peut comprendre une cellule de tissu conjonctif, voire une cellule progénitrice capable de produire des matrices extracellulaires de tissu conjonctif tel que le collagène et le glycosaminoglycane. Des méthodes de traitement de tissu conjonctif défectueux, de lésion cartilagineuse et de dégradation cartilagineuse sont en outre décrites.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNzLEKwjAQgOEuDqK-w4FrC9Yq4nimlyaS5kpz4liLxEm0UN8fRXwAp3_5-KfJxfojKcGDI2CtMzGUQTDkNChsxTqsKAUhX7JPAX0JzlZYkxdoqUHbguK64WDFsg9fUJMYLsNnB6dA82Ry6-9jXPw6S5aaRJksDs8ujkN_jY_46s68XuX7fFdsii3mxX_qDepsM7k</recordid><startdate>20190912</startdate><enddate>20190912</enddate><creator>KELLY, Terri-Ann</creator><creator>HUANG, Angela Hai</creator><creator>BHUMRATANA, Sarindr</creator><creator>BEANE, Olivia Spencer</creator><creator>JEFFRIES, Eric Meade</creator><scope>EVB</scope></search><sort><creationdate>20190912</creationdate><title>INJECTABLE OFF-THE- SHELF CARTILAGE, TENDON, AND LIGAMENT REPAIR COMPOSITIONS AND METHODS OF USE</title><author>KELLY, Terri-Ann ; HUANG, Angela Hai ; BHUMRATANA, Sarindr ; BEANE, Olivia Spencer ; JEFFRIES, Eric Meade</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2019173435A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KELLY, Terri-Ann</creatorcontrib><creatorcontrib>HUANG, Angela Hai</creatorcontrib><creatorcontrib>BHUMRATANA, Sarindr</creatorcontrib><creatorcontrib>BEANE, Olivia Spencer</creatorcontrib><creatorcontrib>JEFFRIES, Eric Meade</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KELLY, Terri-Ann</au><au>HUANG, Angela Hai</au><au>BHUMRATANA, Sarindr</au><au>BEANE, Olivia Spencer</au><au>JEFFRIES, Eric Meade</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INJECTABLE OFF-THE- SHELF CARTILAGE, TENDON, AND LIGAMENT REPAIR COMPOSITIONS AND METHODS OF USE</title><date>2019-09-12</date><risdate>2019</risdate><abstract>Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellular matrices such collagen and glycosaminoglycan. Also provided are methods of treating connective tissue defects, cartilage injury, and cartilage degradation.
L'invention concerne des compositions comprenant un corps de cellule mésenchymateuse condensé et un hydrogel. Les compositions peuvent en outre comprendre des médicaments ou des facteurs de croissance. Le corps de cellule mésenchymateuse condensé peut comprendre une cellule de tissu conjonctif, voire une cellule progénitrice capable de produire des matrices extracellulaires de tissu conjonctif tel que le collagène et le glycosaminoglycane. Des méthodes de traitement de tissu conjonctif défectueux, de lésion cartilagineuse et de dégradation cartilagineuse sont en outre décrites.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | INJECTABLE OFF-THE- SHELF CARTILAGE, TENDON, AND LIGAMENT REPAIR COMPOSITIONS AND METHODS OF USE |
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