SPRAY FORMULATION BASED ON IMMUNOGLOBIN Y ANTIBODIES HAVING TREATMENT AND PROTECTION CHARACTERISTICS FOR ALL STRAINS OF INFLUENZA A VIRUS

The present invention relates to obtaining nano-biotechnologic agent (lgY@PLGA) as a result of encapsulating with poly (lactic-co-glycolic-acid) (PLGA) which is a polymer which does not show toxic effect in the metabolism, in order to prevent specific immuno-globulin Y antibodies from fragmenting be...

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Hauptverfasser: UNAL, Gokce, BUDAMA KILINC, Yasemin
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BUDAMA KILINC, Yasemin
description The present invention relates to obtaining nano-biotechnologic agent (lgY@PLGA) as a result of encapsulating with poly (lactic-co-glycolic-acid) (PLGA) which is a polymer which does not show toxic effect in the metabolism, in order to prevent specific immuno-globulin Y antibodies from fragmenting before reaching their targets in the body and in order to provide specific immuno-globulin Y antibodies to bind to the external region (M2e) of the M2 protein of the influenza A virus which is substantially well-protected and in order to provide deactivation of the viruses, and relates to application of said nano-biotechnologic agent (lgY@PLGA) in spray form. La présente invention concerne l'obtention d'un agent nano-biotechnologique (lgY@PLGA) suite à l'encapsulation avec du poly (acide lactique-co-glycolique) (PLGA) qui est un polymère qui ne présente pas d'effet toxique dans le métabolisme, afin d'empêcher des anticorps immunoglobuline Y spécifiques de se fragmenter avant d'atteindre leurs cibles dans le corps et afin de fournir des anticorps immunoglobuline Y spécifiques à se lier à la région externe (M2e) de la protéine M2 du virus de la grippe A qui est sensiblement bien protégé et afin d'assurer la désactivation des virus, et concerne l'application dudit agent nano-biotechnologique (lgY@PLGA) sous forme de spray.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SPRAY FORMULATION BASED ON IMMUNOGLOBIN Y ANTIBODIES HAVING TREATMENT AND PROTECTION CHARACTERISTICS FOR ALL STRAINS OF INFLUENZA A VIRUS
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