GANGLIOSIDE GM3-CONTAINING NANOPARTICLES AS IMMUNOMODULATORS

The present invention relates to a pharmaceutical composition with an active principle that includes membrane vesicle conjugates of Neisseria meningitidis and the GM3 ganglioside in a conjugation proportion with a protein excess, with special features regarding the size, surface charge and morpholog...

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Hauptverfasser: RUBIO HERNÁNDEZ, María Caridad, CURBELO HAREDIA, Idelmis, MESA PARDILLO, Circe, RÁBADE CHEDIAK, Maura Lisett, AGUIAR GARCÍA, Lena, HERNÁNDEZ DE LA ROSA, Lourdes, RODRÍGUEZ RODRÍGUEZ, Camilo, FERNÁNDEZ MOLINA, Luis Enrique, VALDÉS GUERRERO, Orlando, GRACIA MEDINA, Elias Antonio, FERNÁNDEZ GÓMEZ, Audry, VALDÉS ZAYAS, Anet, PEÑA SÁNCHEZ, Vladimir, PÉREZ RUÍZ, Leslie, OLIVER RÍOS, Liliana, ALVAREZ ARZOLA, Rydell
Format: Patent
Sprache:eng ; fre ; spa
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